RAD 140 MK 677 Stack Guide: Everything You Need to Know

Navigating the world of SARMs can be a daunting task, especially when it comes to stacking. You’ve likely heard of RAD 140 and MK 677, two of the most popular substances in this category. But what happens when you stack them together?

The RAD 140 MK 677 stack is a powerful combination that’s gaining popularity among fitness enthusiasts and bodybuilders. It’s known for its potential to boost muscle growth, enhance recovery, and improve sleep quality.

In this article, we’ll dive into the key benefits and potential side effects of this stack. We’ll also provide insights on how to use it effectively to optimize your fitness results.

Explaining the mechanics behind the RAD 140 MK 677 stack

What is RAD 140 MK 677 Stack?

A RAD 140 MK 677 stack (also known as the testolone and ibutamoren stack) is a powerful combo that bodybuilders and fitness enthusiasts use to boost muscle growth, improve recovery, and enhance sleep quality. The two compounds, RAD 140 and MK 677, when used together, provide synergistic effects that enhance the overall results of your fitness regimen. Let’s dig deeper into what each substance is and how they contribute to this potent stack.

What is RAD-140

RAD-140, also known as Testolone, is a Selective Androgen Receptor Modulator (SARM) which is praised for its muscle-building capabilities. It’s designed to provide the same benefits as anabolic steroids but without the associated side effects. RAD-140 directly targets your skeletal muscles, stimulating them to grow and develop with greater intensity.

Here’s what you need to know about RAD140:

  • It’s highly anabolic, meaning it promotes muscle growth.
  • It has fewer side effects compared to traditional anabolic steroids.
  • RAD-140 has a high affinity for androgen receptors, particularly in skeletal muscles.

What is MK-677

On the other hand, MK-677, or Ibutamoren, is not a SARM, but a Growth Hormone Secretagogue (GHS). This means it stimulates your body to naturally produce more growth hormone. The increased growth hormone release leads to an increase in Insulin-like Growth Factor 1 (IGF-1), a crucial hormone for muscle growth and recovery.

Here are the key points about MK677:

  • It boosts your body’s natural growth hormone production.
  • MK-677 helps in muscle recovery and improves sleep quality.
  • Unlike other GHS, MK-677 does not affect cortisol levels, which means it won’t cause unwanted stress to your body.

When you stack RAD-140 and MK-677 together, you’re utilizing a powerful muscle-building duo. RAD-140 works to directly stimulate muscle growth, while MK-677 promotes recovery and repair by boosting your body’s natural growth hormone production. This combination results in a potent stack that not only enhances muscle growth but also minimizes recovery time and improves sleep, making it a popular choice among fitness enthusiasts.

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Benefits of RAD 140 MK 677 Stack

Stack Benefits

The combination of RAD 140 and MK 677 is a game-changer in the world of SARMs. This dynamic duo is known for its multiple benefits. Let’s delve deeper into why this stack is becoming increasingly popular.

Increased Muscle Mass

RAD 140 and MK 677 are a force to be reckoned with when it comes to muscle growth. RAD 140 has been found to promote muscle growth and increase lean body mass (Leung et al., 2022). Meanwhile, MK 677 increases fat-free mass, giving you a more chiseled look (Nass et al., 2008). Together, they’re a formidable team that could give your muscle mass a significant boost.

Enhanced Strength and Endurance

There’s more to the RAD 140 MK 677 stack than just muscle growth. RAD 140, with its anabolic effects on bones and muscles, can potentially lead to improvements in your strength and endurance (Leung et al., 2022). MK 677, as a growth hormone secretagogue, might also indirectly influence your endurance and strength through its impact on growth hormone secretion (Svensson, 1998).

Improved Athletic Performance

The potential benefits of the RAD 140 MK 677 stack aren’t limited to bodybuilding. RAD 140’s anabolic effects can lead to improvements in your overall athletic performance. MK 677, with its influence on growth hormone secretion, might also play a vital role here (Svensson, 1998). So whether you’re hitting the gym or running a marathon, the RAD 140 MK 677 stack could give you the edge you need.

Accelerated Fat Loss

When it comes to fat loss, the RAD 140 MK 677 stack might be your new best friend. While RAD 140 is known for its ability to increase lean body mass, MK 677 is renowned for its potential to reduce fat mass. This could make the RAD 140 MK 677 stack a powerful tool in your arsenal for achieving a leaner, more ripped physique.

Some users say that MK 677 works best when stacked with Cardarine, which you can read more about on our blog.

How does RAD 140 MK 677 Stack Work?

How it Works

The RAD 140 MK 677 stack operates in a unique, synergistic manner that amplifies the individual effects of each compound. Here’s how:

Diagram showing how stacking RAD 140 with MK 677 leads to joint benefits between both compounds

RAD 140, also known as Testolone, primarily works by selectively targeting androgen receptors in your muscle and bone tissues. This selectivity allows it to promote muscle growth and bone density without the typical androgenic side effects associated with traditional steroids. It’s like getting the benefits of steroids without the drawbacks.

MK 677, or Ibutamoren, on the other hand, works by mimicking the action of the hormone Ghrelin. This triggers the pituitary gland into releasing more growth hormone and IGF-1, which promotes muscle growth, bone density, and metabolism. What’s more, it also improves sleep quality, which is crucial for recovery and growth.

When you combine RAD 140 and MK 677, you’re essentially getting a double whammy of muscle-building action. RAD 140’s targeted anabolic effects, coupled with MK 677’s growth hormone boost, create a powerful combination that can significantly enhance your muscle growth, strength, and recovery.

Now you might be wondering, “Is this stack safe?” Well, while both RAD 140 and MK 677 have demonstrated a good safety profile in clinical studies, it’s important to remember that everyone’s body reacts differently. Always consult with a healthcare professional before starting any new supplement regimen. Out of the two, RAD is more likely to cause side effects, which you can read about here.

Dosage and Cycle for RAD 140 MK 677 Stack

Dosage + Cycle Length

Knowing how to optimize the correct dosage is crucial for achieving the best results. Let’s dive into the dosage and cycle details of this powerful stack.

RAD 140 Dosage

With RAD 140, it’s all about starting low and gradually increasing the dosage as your body adapts. Initially, you might want to start with 10mg per day. Over time, as your body gets used to the compound, you could increase the dosage up to 20mg per day. Remember, it’s not about how much you take, but how well your body responds to it. Always pay attention to your body and adjust accordingly. Read our guide on RAD 140 dosage here.

MK 677 Dosage

On the other hand, MK 677 has a more straightforward dosage approach. A standard dose usually falls within the 20-25mg per day range. This dosage is often enough to boost growth hormone production and improve sleep. There’s no need to split the dosage throughout the day; you can take it all at once, preferably before bed to maximize its sleep-enhancing benefits. Read our full MK 677 dosage guide here.

Cycle Length

Let’s talk about the cycle length. A cycle is the period during which you’re taking these supplements. When it comes to the RAD 140 MK 677 stack, a typical cycle length ranges from 8 to 12 weeks. This duration allows your body enough time to experience the benefits while minimizing potential side effects. However, your cycle length might vary depending on your individual goals and tolerance levels.

Post Cycle Therapy (PCT)

After the cycle, it’s essential to undergo a Post Cycle Therapy, or PCT. This process helps your body regain its natural hormonal balance and recover from the intense training period. A standard PCT usually lasts 4 to 6 weeks. You might want to consider natural supplements like Nolvadex or Clomid to aid in recovery. Read our RAD 140 PCT guide here.

And there you have it – the basic guidelines for dosing and cycling the RAD 140 MK 677 stack. Remember, these are just guidelines. Individual results may vary, and it’s always best to consult with a healthcare professional before starting any new supplement regimen.

Potential Side Effects of RAD 140 MK 677 Stack

Side Effects

While RAD 140 MK 677 stack is a promising combo for muscle growth and performance enhancement, it’s also vital to be aware of the potential side effects. Let’s delve into some of them.

First off, RAD 140 may cause some temporary hormonal imbalances.

  • You might experience mood swings.
  • Some users reported high blood pressure.
  • There’s a chance of testosterone suppression, hence the need for a post cycle therapy (PCT).

On the other hand, MK 677 can lead to an increase in appetite. This can be beneficial if your goal is to gain weight, but could be a setback if you’re trying to lose fat. It’s also worth noting that MK 677 may cause a slight increase in blood sugar levels and could lead to lethargy.

In addition, both RAD 140 and MK 677 might cause mild to moderate headaches and nausea in some users.

As with any supplement regimen, individual responses can vary. It’s crucial to listen to your body and adjust dosages as needed. Remember, it’s always best to consult with a healthcare professional before starting any new supplement regimen.

While this information might seem overwhelming, don’t let it deter you. Knowledge is power, and being aware of these potential side effects will allow you to make an educated decision about whether the RAD 140 MK 677 stack is the right choice for your fitness goals.

Precautions and Considerations before starting


When delving into the world of performance enhancement supplements like the RAD 140 MK 677 stack, it’s crucial to take certain precautions and considerations into account. Your health and well-being are of utmost importance, and these should never be compromised for the sake of muscle growth or performance.

Consultation with a Healthcare Professional

First and foremost, always consult with a healthcare professional before starting any new supplement regimen. They’ll assess your overall health status and help you understand if your body can handle the impact of these potent compounds. Remember, individual responses can vary significantly, and what works for one person might not work for you.

Understanding the Potential Risks

It’s essential to have a clear understanding of the potential risks associated with RAD 140 and MK 677. As mentioned earlier, RAD 140 may lead to hormonal imbalances, mood swings, high blood pressure, and testosterone suppression. On the other hand, MK 677 can increase your appetite, elevate blood sugar levels, and cause lethargy. Both these compounds may also result in headaches and nausea.

While these side effects sound concerning, it’s worth noting that not everyone experiences them. However, being aware of these risks will help you spot any adverse effects early and take appropriate action.

Monitoring and Adjusting Dosage

When using supplements like the RAD 140 MK 677 stack, it’s important to monitor your body’s response closely. Keep a check on any changes, whether positive or negative.

If you notice any adverse effects, it may be necessary to adjust your dosage or discontinue the use of these supplements altogether. Don’t hesitate to reach out to your healthcare provider in such a case.

While the RAD 140 MK 677 stack can offer significant benefits in terms of muscle growth and performance enhancement, it’s important to approach its use with caution and mindfulness. Stay safe and remember, your health always comes first.

Where to Buy RAD 140 MK 677 Stack

Recommended Sources

If you’re considering adding RAD 140 and MK 677 to your supplement regimen, you’ll want to make sure you’re sourcing them from a reputable seller. It’s crucial to ensure the quality and safety of these products. Let’s explore a couple of the top online vendors where you can purchase RAD 140 MK 677 stack.


One of the most trusted sources for purchasing RAD 140 and MK 677 is Chemyo. This company has established a solid reputation in the market for their high-quality products. All their items go through rigorous third-party testing for purity and concentration levels. You can be assured that you’re getting exactly what’s listed on the label.

Chemyo offers worldwide shipping, so no matter where you’re located, you’ll be able to take advantage of their top-notch products. Their customer service is also highly praised, with a responsive and knowledgeable team ready to assist you with any questions or concerns.

Sports Technology Labs

Another great place to buy RAD 140 MK 677 stack is Sports Technology Labs. This vendor is well-known for their commitment to quality. They offer pharmaceutical-grade products that have been tested for purity and potency.

What sets Sports Technology Labs apart is their focus on customer education. They believe in empowering their customers with knowledge about their products, the science behind them, and how to use them most effectively. This approach helps you make informed decisions about your supplement use.

Both Chemyo and Sports Technology Labs are reliable sources for purchasing RAD 140 and MK 677. Remember, always monitor your body’s reactions and adjust your dosages accordingly. And of course, consult with a healthcare professional if you’re unsure about anything.

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Frequently Asked Questions


What can I expect when using the mk-677 rad-140 stack?

When using this stack, you can notice an increase in lean muscle, strength in the gym, and potentially even some fat loss results. It’s a potent combination of two potent SARMS that are often used by people serious about bodybuilding. However, always remember to take the correct dosage and consult a professional if you’re a first time user.

Is there any water retention with the use of mk-677 in this stack?

Yes, when using mk677 in this stack, an increase in water retention is typical. It’s essentially a result of the growth hormone mimicking behavior of MK-677, which can lead to increased water retention. MK-677 will not increase cortisol, the body’s stress hormone.

Does MK-677 act like SARMs and for anabolic effects?

Even though MK-677 is often classified with SARMS, it’s important to understand that mk677 is not a SARM. It acts as a growth hormone secretagogue and doesn’t interact with the androgen receptors like a SARM, such as RAD-140 or Ostarine, would.

Should I take PCT after an MK-677 RAD-140 cycle?

Yes, it’s recommended to take PCT after the cycle. Even if MK-677 doesn’t cause suppression, when using it with RAD140, you must remember that rad140 can cause suppression and it’s key to help your body get back to its normal hormone levels after the cycle.

Is there a risk when combining MK-677 and Rad-140?

When you combine mk-677 and rad-140, you do need to know what you’re doing and take the right precautions. Both of these compounds have been developed for research purposes and aren’t as studied as traditional anabolic steroids. Always start with a lower dose and increase as needed, monitoring your body’s response.

How do I use the The MK677 RAD140 MK-677 Stack?

First and foremost, follow the instructions provided by the manufacturer or your trained professional. A bottle of rad-140 typically contains rad140 at a set concentration. The usual dosage is around 10mg of rad 140 per day and the mk-677 dosage being around 20mg per day. But remember, your first cycle should always be lighter to check your body’s response.

How long does a cycle of mk-677 rad-140 stack last?

Generally, a cycle of mk-677 rad-140 stack lasts around 8 weeks. However, the specific length of a cycle may vary from person to person based on individual fitness goals and responses to the stack.

Will the RAD140 MK-677 stack help me get bigger biceps?

Yes, using the RAD 140 MK 677 stack can help strengthen your biceps and increase their size. RAD 140 or Testolone is known to be very potent and can aid in muscle growth and strength. Coupled with MK-677 or Ibutamoren, which improves quality of sleep and nutrition absorption, can provide substantial results for muscle growth.

Does the mk-677 rad-140 help with lean mass and stamina?

Yes, mk-677 rad-140 is best known for its effectiveness in building lean mass and enhancing stamina. These benefits are produced due to the anabolic nature of RAD-140 and the growth hormone mimicking behavior of MK-677, which usually results in increased muscle mass and strength.

Where can I find reliable information about the RAD 140 MK 677 stack?

There are numerous resources available online to learn about the RAD 140 MK 677 stack. But it’s important to choose a source that presents objective, scientific information. Sarms.io is a reputable source of information about use of SARMS and other related topics.

Wrapping up: final thoughts, conclusions, and references


Navigating the world of supplements like the RAD 140 MK 677 stack can be complex, but you’re now equipped with the knowledge to make informed decisions. It’s crucial to remember the potential side effects of RAD 140 and MK 677. Adjusting dosages to your body’s reactions and seeking professional advice when necessary can help mitigate these risks. Always prioritize purchasing from trusted sellers like Chemyo and Sports Technology Labs, ensuring you’re getting the quality you deserve. Remember, your health and safety should always come first when aiming for muscle growth and performance enhancement.


  1. Barbara, Mary, et al. “Drug-induced liver injury associated with alpha bolic (rad-140) and alpha elite (rad-140 and lgd-4033)“. Acg Case Reports Journal, vol. 7, no. 6, 2020, p. e00409.
  2. Copinschi, Georges, et al. “Prolonged oral treatment with mk-677, a novel growth hormone secretagogue, improves sleep quality in man“. Neuroendocrinology, vol. 66, no. 4, 1997, p. 278-286.
  3. Cutler, Charlotte, et al. “Identification of equine in vitro metabolites of seven non‐steroidal selective androgen receptor modulators for doping control purposes“. Drug Testing and Analysis, vol. 14, no. 2, 2021, p. 349-370.
  4. Lee, Jung-Hun, et al. “Effect of the orally active growth hormone secretagogue mk-677 on somatic growth in rats“. Yonsei Medical Journal, vol. 59, no. 10, 2018, p. 1174.
  5. Leung, Kenneth, et al. “Rad-140 drug-induced liver injury“. Ochsner Journal, vol. 22, no. 4, 2022, p. 361-365.
  6. Mohamed, Wael, et al. “Selective androgen receptor modulators (sarms)-induced liver injury: a case report and review of literature“. Cureus, 2023.
  7. Murphy, M., et al. “Oral administration of the growth hormone secretagogue mk‐677 increases markers of bone turnover in healthy and functionally impaired elderly adults“. Journal of Bone and Mineral Research, vol. 14, no. 7, 1999, p. 1182-1188.
  8. Padappayil, Rana, et al. “Acute myocarditis from the use of selective androgen receptor modulator (sarm) rad-140 (testolone)“. Cureus, 2022.
  9. Solomon, Z.J., et al. “Selective androgen receptor modulators: current knowledge and clinical applications“. Sexual Medicine Reviews, vol. 7, no. 1, 2019, p. 84-94.
Chris Jackson
Chris Jackson

Chris Jackson, co-founder of Sarms.io, is a renowned fitness blogger, physique model, and evolutionary bioscience researcher specializing in SARMs (Selective Androgen Receptor Modulators). His extensive work, characterized by cutting-edge research and practical training advice, has made Sarms.io a leading source for accurate, credible information on performance enhancers. With a dedication to improving the understanding and application of SARMs in optimizing human performance, his contributions have not only expanded public awareness but also shaped the conversation around these substances. Chris's pursuit of knowledge and commitment to sharing it continue to inspire many in their fitness journeys.

  1. I was wondering why it says 2 different cycle dosages for the RAD140 dosage guide and MK-677 dosage guide versus your dosage guide here? Are you able to handle a higher dose with less negative affects while stacked?

  2. Do I take RAD140 and MK677 even on days I don’t lift?

  3. Is it ok to run 200mg of test cypionate weekly with this stack ?

  4. Will this stack cause any acne?

    • It’s rare to experience acne as a side effect of this stack. MK 677 actually improves skin health through collagen production

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