RAD 140 Suppression: How To Prevent it On Cycle

As far as selective androgen receptor modulators or SARMs go, RAD 140 is one of the strongest. Also known as Testolone, it was created as a safer alternative for testosterone replacement therapy.

Medically, the interest in this SARM is because it can help prevent wasting of the muscle that comes from some diseases. But it is also useful in building muscle mass and as a performance enhancer.

It is one of the strongest SARMs out there and you will see the results after using it for a week. The flip side of the coin is that stronger = more suppression. That is why you need post-cycle therapy.
PCT is a process where you go off the drug for a while (depending on the usage and length of the cycle) so that your body can come back to equilibrium.

This post will discuss the expected testosterone suppression from using RAD 140. We’ll discuss why it happens, and give you some insider tips to prevent it as much as possible.

Why does suppression happen when you take SARMs?

< class="mt0 mb10 font200" style="color:#0b3954;"> About Suppression

As is the case with all SARMs, RAD140 will signal the androgen receptors in your muscle tissue. This is a good thing; it’s how SARMs allow you to build so much muscle.

However, there is a negative result of this signaling. Your body will think that because it’s androgen recpetors are stimulated that you already have enough testosterone in your system. To prevent over stimulation, it will stop producing testosterone on its own.

This testosterone suppression comes along with slight decreases of LH (leutinizing hormone) levels. To put it in simple terms, you are temporarily replacing testosterone with RAD 140 (a much more anabolic hormone). After you stop taking the SARMs, your body will have a lower baseline testosterone level.

How long does it take to start feeling suppressed


Typically, RAD140 cycles last from six to eight weeks. You should not run it longer than that. Since this is a powerful compound, you don’t want to take more than 20 mg per day. The preferred dosage starts at 5 mg and goes up to 10 mg per day.

The suppression element enters towards the end during the sixth and seventh weeks. If it happens before that, it means that you have been taking more than what your body can handle, meaning 20 or 30 mg per day.

In that case, dial your dosage back. You’re probably using too high of a dose. There are far too many people recommending doses that are way too high. Even at lower doses, you will need post cycle therapy, which we will get to in a minute.

What does being suppressed from RAD 140 feel like?


When you are experiencing RAD140 suppression, you will experience the following symptoms:

  • Brain fog
  • Lethargy
  • Loss of libido (depending on the person)

Extreme lethargy is terrible, and many lose the will to do anything, including hitting the gym. Every activity starts to feel like a chore which is uncomfortable and brings the mood down.

The lack of motivation might also tinker with your moods. This might have an impact on your workout routine too. This is true because it is known to cause hair loss, fatigue and mood swings.

However, keep an eye out for other symptoms since it affects different people in different ways. The best way is to track your progress on a daily basis by keeping a journal.

There isn’t too much information on the side effects of RAD140 for the lack of scientific studies, except anecdotal evidence. Research is still underway on whether it can help with fighting breast cancer and protecting brain cells.

Studies have shown that RAD140 helps with increasing muscle weight at a dose that is lower than other SARMs. It is also quite potent when given to non-human primates. So apart from rats, it has also been tested on monkeys and the overall profile was very good. Those toxicology reports are often used to extrapolate RAD140’s impact on human beings.

Like some other SARMs there are two cycles in which these drugs should be taken. One is the cutting cycle and the other is the bulking cycle. While SARMs like ostarine are preferred during the cutting cycles because it is more effective for fat loss. SARMs like RAD140 are better for building muscles. So, they are more impactful during the bulking cycle.

Temoxifen citrate, also known as Nolvadex.

PCT Protocol for RAD 140 Cycles


The good news is that the PCT process for SARMs is a breeze compared to anabolic steroids. Assuming you follow the protocol correctly, you should not have any bad side effects. I have run plenty of SARMs only cycles myself, and I’ve never felt like I lost any of my progress when I finished PCT.

You can see the full RAD 140 PCT guide on the blog.

Some people swear by over the counter PCT supplements, while others say they’re trash. Ultimately, it depends on what product you are using. Look for companies that use lab tested ingredients and refer to examine.com to research the appropriate dosages.

Tips to avoid Post-Cycle Therapy: follow these tricks

Avoiding PCT

While PCT is highly recommended for RAD140 users, there are ways to keep it under control or avoid it entirely if the circumstances don’t allow for it. Here is what you need to do in that scenario.

This is an SARM that is meant for eight weeks. Don’t get greedy. After eight weeks, even if you keep going, you will not see much muscle gain. So, you are likely to experience an uncomfortable wave of suppression.

Beginners should strictly stay with 5 mg per day and monitor their body’s reaction to the dosage. If it feels fine, you can go to the next level, which is 10 mg per day. If you go over that, you will not just head towards post-cycle therapy but might also have to abandon the cycle altogether. Excess RAD140 leads to suppression, not more muscles.

Use a Good Source

Procuring high-quality compounds is a very important part of taking SARMs. Since many of them are banned for health reasons, a lot of these products are available only for underground fitness industry individuals. So, you should be cautious of fake products because there are a lot of them.

Plenty of them are actually steroids and prohormones which do a ton of damage and not good at all. If you jump into this without proper guidance and some amount of research on your own, you are headed towards danger. Such mistakes can lead to irreversible side effects apart from crushing suppression.

💡 Top RAD 140 Sources in 2024

Looking for pure Testolone? Buy high purity RAD 140, YK 11, MK 677 and LGD 4033 from one of the stores in the Verified Sources list.

Plenty of them are actually steroids and prohormones which do a ton of damage and not good at all. If you jump into this without proper guidance and some amount of research on your own, you are headed towards danger. Such mistakes can lead to irreversible side effects apart from crushing suppression.

You can look for reliable SARMs sources here.

If you are still in the planning stages, consider getting a blood test done before you start using RAD140. This way, you get to gauge how your body is reacting to the compound. It will also help you keep a track of suppression and give you a heads up if you need to stop.

Frequently Asked Questions


How suppressive is RAD 140?

RAD 140 is considered to be one of the most suppressive SARMs on the market today. With that said, It is not as suppressive on testosterone levels as traditional anabolic steroids.

Does RAD 140 shut you down hard?

While you will experience a temporary dip in natural testosterone levels while taking RAD 140, you will not be “shut down”. Most users are back to baseline levels after 4 to 6 weeks off.

Can I use RAD 140 on TRT?

Yes, it’s actually more common than you think. Since you are already replacing your natural testosterone levels, you will not have to worry about low T after your cycle ends.

Is TLB-150 more suppressive than RAD-140?

Currently, there is limited information available on TLB-150 (RAD-150) since it is a relatively new and under-researched SARM. As a result, it is not possible to definitively determine whether TLB-150 is more suppressive than RAD-140. More research is needed to understand the effects and potential side effects of TLB-150, including its level of suppression compared to RAD-140 or other SARMs.

Parting Words

RAD 140 is not a compound you can hit hard for longer than 8 weeks. So, it is best to follow the guidelines listed above and keep as far away from side effects to save time, money and quite literally, your energy.

Have you had experience with RAD 140 on your cycle? Let us know in the comments section below and tell us how you dealt with it. Feel free to ask any questions if you feel that we left anything out!

Chris Jackson
Chris Jackson

Chris Jackson, co-founder of Sarms.io, is a renowned fitness blogger, physique model, and evolutionary bioscience researcher specializing in SARMs (Selective Androgen Receptor Modulators). His extensive work, characterized by cutting-edge research and practical training advice, has made Sarms.io a leading source for accurate, credible information on performance enhancers. With a dedication to improving the understanding and application of SARMs in optimizing human performance, his contributions have not only expanded public awareness but also shaped the conversation around these substances. Chris's pursuit of knowledge and commitment to sharing it continue to inspire many in their fitness journeys.

  1. If I decide I want to stop taking Rad after 2 1/2 weeks at 30-40 mgs a dose. Would I be safe to stop it and start taking tamoxifen say tomorrow?

    • Yes, that’s probably a good idea. 40mgs is a huge dose.

      Tamoxifen should be fine. Enclomiphene would be better though

  2. Rad 140 will decimate your natural testosterone and it will do it quick. After a 6 week cycle I went from 890 ng/dl of test down to 75 ng/dl.
    Now that being said, I did no PCT after, just kept eating healthy, kept exercising, and after 6 weeks off Rad 140 I was back to my normal T levels. However I’m a healthy 29 year old male. If you are older, your natural T will have a harder time recovering.

    • If I decide I want to stop taking Rad after 2 1/2 weeks at 30-40 mgs a dose. Would I be safe to stop it and start taking tamoxifen say tomorrow?

  3. Hi Mate,

    Currently around the middle of my Rad 140 cycle. these are my bloods. How much suppression do you think one should abandon the cycle?

    Let me know you thoughts.

    I’m Obviously suppressed but with no symptoms, feel great.

    Blood work Prior (nmol/l)
    Test 21
    SHBG 40
    Free T 410

    Mid 6w
    Test 7.4
    SHBG 9
    Free T 21

  4. So you’re saying that if you stay below 10mg there should be no need for a PCT afterwards, correct?

  5. Took 20 mg and in 2 weeks the lethargy kicked in. I stagged with 10 mg of lgd4 and I dipped hard too quick. Should have read this in preparation and not desparation.

    • 20mg is a lot of RAD if you’re stacking it with other compounds. Try 5mg and 5mg for a week and the crank it up to 10/10

  6. Do you loose a lot of your gains that you’ve accomplished after the cycle finishes ?

    • I’ve been taking 10mg of Rad140 for 8 weeks, i’m 58 and it has in some ways rejuvenated me. I have more focus, better moods, rare bouts of depression (i have suffered from depression for 15yrs) . Body is looking lean with no weight loss.
      Side effects, not much, tiredness maybe, recent back ache but i think this maybe down to my training schedule.
      I train 5/6 days per week 3x 2 hr weights and 3 x Thai boxing. Intense session no messing about.
      Bottom line i want to run this for the rest of my life because its changed my life in the last 8 weeks. Can I?

      • At your age I would just hop on prescription TRT or self administer. I wouldn’t recommend taking RAD 24/7/365 due to potential liver/kidney strain.

        Hop on TRT, 6 weeks on, 4 weeks off.

        • Well I was using it 8 weeks of rad with 2 pills a day and than I finished and hop
          On pct for a month now I’m about to finish so I’m just curious can I start an other 8weeks and hop in pct and not using it at all ? Does that effect permanent suppression on my test level ?

  7. Thoughts on suppression risk @5mg of rad for 6-8 weeks?
    Also, what labs, other than test and liver and kidney panels would be worth checking?

  8. Awesome just what I was looking for

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