LGD 4033
LGD-4033, also known as ligandrol or anabolicum, is a selective androgen receptor modulator (SARM) that binds to androgen receptors in the body, leading to anabolic effects on muscle and bone tissue [1]. LGD-4033 has been shown to increase bone mineral density, bone formation, and bone strength in preclinical models [4]. It is commercially available as a supplement product and is becoming increasingly popular among athletes due to its promising anabolic effects [5]. However, its use is banned by WADA [5]. LGD-4033 has been shown to increase skeletal muscle mass without commensurate improvements in muscular strength and function [3]. It has also been investigated in clinical trials for increasing bone strength in healthy young men [4]. The presence of a cyano group in LGD‐4033 instead of a nitro group improves the half‐life of the compound [7].
LGD 4033 Beginners Guide

CAS: 1165910-22-4
Molecular Weight: 338.25 g/mol
Chemical formula: C14H12F6N2O
Chemical name: 4-[(2R)-2-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]pyrrolidin-1-yl]-2-(trifluoromethyl)benzonitrile
Type: Selective Androgen Receptor Modulator

PROS:

  • Promotes muscle growth and strength
  • Enhances fat loss and body composition
  • Increases bone density and durability

CONS:

  • May cause temporary testosterone suppression

LGD 4033 For Sale

Dive into our curated list of LGD 4033 sources, chosen for their high-quality products and secure shipping. Trust our expertise as we guide you towards harnessing the muscle-building and fat-shedding benefits of LGD 4033. Embark on your fitness journey with confidence, backed by the most reliable providers in the industry.

Sports Technology Labs

30ml of liquid LGD solution at 10mg/ml. Use code sarmsdotio for 15% off your entire purchase at STL!
$54.99$64.99
Paradigm Peptides LGD 4033 capsules

Paradigm Peptides Capsules

60 capsules at 10mg each = 600mg total
$59.00
Behemoth Labz LGD 4033

Behemoth Labz

Use code BHM31 for 10% off your entire purchase at Behemoth Labz!
$44.98$49.99
LGD4033 from Science.bio

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Pre-orders are live at Science.bio. Use code christopher10 to save 10% off your entire order.
$39.99$50.00

You can view the full list of verified sources here

References:

  1. Thevis, Lagojda, Kuehne, Thomas, Dib, Hansson, … & Schänzer (2015). Characterization of a non-approved selective androgen receptor modulator drug candidate sold via the Internet and identification ofin vitrogenerated phase-I metabolites for human sports drug testing. Rapid Commun. Mass Spectrom., 11(29), 991-999.
  2. Wagener, Guddat, Görgens, Angelis, Petrou, Lagojda, … & Thevis (2021). Investigations into the elimination profiles and metabolite ratios of micro-dosed selective androgen receptor modulator LGD-4033 for doping control purposes. Anal Bioanal Chem, 2(414), 1151-1162.
  3. Cardaci, Machek, Wilburn, Heileson, Harris, Cintineo, … & Willoughby (2022). LGD‐4033 and MK‐677 use impacts body composition, circulating biomarkers, and skeletal muscle androgenic hormone and receptor content: A case report. Experimental Physiology, 12(107), 1467-1476.
  4. Bhasin (2015). SELECTIVE ANDROGEN RECEPTOR MODULATORS AS FUNCTION PROMOTING THERAPIES. J Frailty Aging, 1-2.
  5. Pitsinos, Angelis (2022). Structure revision and chemical synthesis of ligandrol’s main bishydroxylated long-term metabolic marker. Org. Biomol. Chem., 46(20), 9112-9116.
  6. Vajda, Hogue, Griffiths, Chang, Burnett, Chen, … & Meglasson (2009). Combination Treatment With a Selective Androgen Receptor Modulator q(SARM) and a Bisphosphonate Has Additive Effects in Osteopenic Female Rats*. Journal of Bone and Mineral Research, 2(24), 231-240.
  7. Geldof, Pozo, Lootens, Morthier, Eenoo, Deventer (2016). In vitro metabolism study of a black market product containing SARM LGD-4033. Drug Test. Analysis, 2(9), 168-178.
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