LGD 4033
LGD-4033, also known as ligandrol or anabolicum, is a selective androgen receptor modulator (SARM) that binds to androgen receptors in the body, leading to anabolic effects on muscle and bone tissue [1]. LGD-4033 has been shown to increase bone mineral density, bone formation, and bone strength in preclinical models [4]. It is commercially available as a supplement product and is becoming increasingly popular among athletes due to its promising anabolic effects [5]. However, its use is banned by WADA [5]. LGD-4033 has been shown to increase skeletal muscle mass without commensurate improvements in muscular strength and function [3]. It has also been investigated in clinical trials for increasing bone strength in healthy young men [4]. The presence of a cyano group in LGD‐4033 instead of a nitro group improves the half‐life of the compound [7].
LGD 4033 Beginners Guide

CAS: 1165910-22-4
Molecular Weight: 338.25 g/mol
Chemical formula: C14H12F6N2O
Chemical name: 4-[(2R)-2-[(1R)-2,2,2-trifluoro-1-hydroxyethyl]pyrrolidin-1-yl]-2-(trifluoromethyl)benzonitrile
Type: Selective Androgen Receptor Modulator

PROS:

  • Promotes muscle growth and strength
  • Enhances fat loss and body composition
  • Increases bone density and durability

CONS:

  • May cause temporary testosterone suppression

LGD 4033 For Sale

Dive into our curated list of LGD 4033 sources, chosen for their high-quality products and secure shipping. Trust our expertise as we guide you towards harnessing the muscle-building and fat-shedding benefits of LGD 4033. Embark on your fitness journey with confidence, backed by the most reliable providers in the industry.

Biaxol Supplements 💳 PAY WITH CREDIT CARD

60 capsules dosed at 10mg each. Use code sarmsio for 10% off your entire order!
$4550
Chemyo liquid LGD 4033

Chemyo

50ml of liquid LGD 4033 solution at 10mg/ml. Use code sarmsdotio for 15% off your entire purchase at Chemyo!
$68.9879.99

Sports Technology Labs

30ml of liquid LGD solution at 10mg/ml. Use code sarmsdotio for 15% off your entire purchase at STL!
$54.99$64.99
Paradigm Peptides LGD 4033 capsules

Paradigm Peptides

60 capsules at 10mg each = 600mg total
$59.00
Behemoth Labz LGD 4033

Behemoth Labz

Use code BHM31 for 10% off your entire purchase at Behemoth Labz!
$44.98$49.99
LGD4033 from Science.bio

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Pre-orders are live at Science.bio. Use code christopher10 to save 10% off your entire order.
$39.99$50.00

You can view the full list of verified sources here

References:

  1. Thevis, Lagojda, Kuehne, Thomas, Dib, Hansson, … & Schänzer (2015). Characterization of a non-approved selective androgen receptor modulator drug candidate sold via the Internet and identification ofin vitrogenerated phase-I metabolites for human sports drug testing. Rapid Commun. Mass Spectrom., 11(29), 991-999.
  2. Wagener, Guddat, Görgens, Angelis, Petrou, Lagojda, … & Thevis (2021). Investigations into the elimination profiles and metabolite ratios of micro-dosed selective androgen receptor modulator LGD-4033 for doping control purposes. Anal Bioanal Chem, 2(414), 1151-1162.
  3. Cardaci, Machek, Wilburn, Heileson, Harris, Cintineo, … & Willoughby (2022). LGD‐4033 and MK‐677 use impacts body composition, circulating biomarkers, and skeletal muscle androgenic hormone and receptor content: A case report. Experimental Physiology, 12(107), 1467-1476.
  4. Bhasin (2015). SELECTIVE ANDROGEN RECEPTOR MODULATORS AS FUNCTION PROMOTING THERAPIES. J Frailty Aging, 1-2.
  5. Pitsinos, Angelis (2022). Structure revision and chemical synthesis of ligandrol’s main bishydroxylated long-term metabolic marker. Org. Biomol. Chem., 46(20), 9112-9116.
  6. Vajda, Hogue, Griffiths, Chang, Burnett, Chen, … & Meglasson (2009). Combination Treatment With a Selective Androgen Receptor Modulator q(SARM) and a Bisphosphonate Has Additive Effects in Osteopenic Female Rats*. Journal of Bone and Mineral Research, 2(24), 231-240.
  7. Geldof, Pozo, Lootens, Morthier, Eenoo, Deventer (2016). In vitro metabolism study of a black market product containing SARM LGD-4033. Drug Test. Analysis, 2(9), 168-178.
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