Andarine (S4), also known as GTx-007, is a selective androgen receptor modulator (SARM) developed by GTx, Inc. for the treatment of muscle wasting, osteoporosis, and benign prostatic hypertrophy [3]. It is also commonly used as a doping substance in sports [5]. In human dermal fibroblasts, andarine has been found to inhibit UVB-induced Smad7 protein expression and elevate total collagen content [2]. Andarine has also been found to inhibit growth, migration, and proliferation while inducing apoptosis in lung cancer cells [6].

Ultimate S4 Andarine guide by

CAS: 401900-40-1
Molecular Weight: 441.36 g/mol
Chemical formula: C19H18F3N3O6S
Chemical name: (2S)-3-(4-acetamido-phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamide
Type: Selective Androgen Receptor Modulator


  • Increases muscle mass and strength
  • Promotes fat loss and improved body composition
  • Enhances bone density and health
  • Supports muscle preservation during cutting


  • May cause temporary vision disturbances
  • Potential for mild testosterone suppression

S4 Andarine For Sale

Step into our expertly assembled collection of S4 Andarine sources, selected for their top-notch products and dependable delivery. Let our knowledge guide you in leveraging the powerful muscle-building and fat-reducing effects of Andarine. Embark on a transformative fitness adventure, backed by the credibility of the industry’s finest providers.

S4 available from Biaxol Supplements

Biaxol Supplements 💳 Pay With Credit Card

60 capsules dosed at 25mg each. Use code sarmsio for 10% off your entire order!
Sports Technology Labs GW 501516

Sports Technology Labs

30ml of Andarine solution at 50mg/ml. Use code sarmsdotio for 15% off your entire purchase at STL!
Chemyo Andarine

Chemyo Best Value

50ml of liquid S4 solution at 50mg/ml. Use code sarmsdotio for 10% off your entire purchase at Chemyo!
Paradigm Peptides S4 Andarine Capsules

Paradigm Peptides Capsules

60 capsules at 12.5mg each = 750mg total
600mg Liquid Cardarine solution from They're Back!

Pre-orders are live at Use code christopher10 to save 10% off your entire order.
Liquid Andarine from Behemoth Labz

Behemoth Labz

Use code BHM31 for 10% off your entire purchase at Behemoth Labz!

You can view the full list of verified sources here


  1. Cawley, Smart, Greer, Lau, Keledjian (2015). Detection of the selective androgen receptor modulator andarine (S-4) in a routine equine blood doping control sample. Drug Test. Analysis, 2(8), 257-261.
  2. Wu, Lin, Hou, Chang, Wen, Lin, … & Chiang (2019). 1,2-Bis[(3-Methoxyphenyl)Methyl]Ethane-1,2-Dicarboxylic Acid Reduces UVB-Induced Photodamage In Vitro and In Vivo. Antioxidants, 10(8), 452.
  3. Perrenoud, Grundisch, Baume, Saugy, Nicoli (2016). Risk of false positive results to SARM S-4 in case of therapeutic use of antineoplastic/antiandrogen drug containing flutamide: a case study. Drug Test. Analysis, 11-12(8), 1109-1113.
  4. Meijer, Bussink, Zatovicova, Span, Lok, Supuran, … & Kaanders (2014). Tumor Microenvironmental Changes Induced by the Sulfamate Carbonic Anhydrase IX Inhibitor S4 in a Laryngeal Tumor Model. PLoS ONE, 9(9), e108068.
  5. Miklos, Vescan, Farczadi, Imre, Vari, Muntean (2019). Development of an Analytical Methodology for the Qualitative and Quantitative Characterization of Capsules with Andarine, in Order to Use them to Investigate the Pharmacotoxicological Profile of the Substance. Rev. Chim., 8(70), 2759-2763.
  6. Demircan (2023). Andarine Plays a Robust In-vitro Anti-carcinogenic Role on A549 Cells Through Inhibition of Proliferation and Migration, and Activation of Cell-cycle Arrest, Senescence, and Apoptosis.
  7. Saber, Bruin, O’Dwyer, H, Rezania, Kieffer (2018). Sex Differences in Maturation of Human Embryonic Stem Cell–Derived β Cells in Mice. Endocrinology, 4(159), 1827-1841.
  8. Smith-Maxwell, Ledwell, Aldrich (1998). Role of the S4 in Cooperativity of Voltage-dependent Potassium Channel Activation. The Journal of General Physiology, 3(111), 399-420.
  9. Sheets, Hanck (2003). Molecular Action of Lidocaine on the Voltage Sensors of Sodium Channels. The Journal of General Physiology, 2(121), 163-175.
  10. Feder, Dagan, Mor (2000). Structure-Activity Relationship Study of Antimicrobial Dermaseptin S4 Showing the Consequences of Peptide Oligomerization on Selective Cytotoxicity. Journal of Biological Chemistry, 6(275), 4230-4238.