RAD 140 With TRT: A Comprehensive Guide to Enhancing Your Testosterone Regimen

The use of Selective Androgen Receptor Modulators (SARMs) alongside Testosterone Replacement Therapy (TRT) has recently surged in popularity, especially in the world of bodybuilding and fitness. Among these, RAD 140 with TRT has emerged as a particularly beneficial combination.

SARMs like RAD 140 work by selectively binding to androgen receptors, while TRT is commonly used to treat low testosterone levels. The integrated approach of using RAD 140 with TRT potentially offers a wide range of health and performance benefits.

Whether you are a seasoned bodybuilder seeking an edge or someone dealing with testosterone-related issues, this information is critical. In this article, we will delve into what you need to know about the benefits of RAD 140 with TRT and why it’s become a buzzword among fitness enthusiasts and health experts alike. 

Key Takeaways
  • 💊 RAD 140 is a popular SARM used for building lean muscle tissue and strength. When taken by itself, it is known to suppress natural testosterone levels.
  • 💉 Users on TRT have better results with RAD 140 as their testosterone levels will not drop but rise due to reduction of SHBG.
  • 🔄 RAD 140 decreases SHBG which in turn increases free testosterone. For users on TRT, this effect lasts throughout the RAD 140 cycle.
  • 👍 Potential benefits of RAD 140 while on TRT include increased motivation, increased libido, better erections, and more energy.
  • 🚫 Possible side effects include acne, hair shedding, and gynecomastia, especially in men prone to these conditions.
  • 🛡️ RAD 140 users on TRT will not require a Post Cycle Therapy (PCT) as they receive testosterone through injections.

What are the effects of adding RAD 140 to a TRT cycle?

Effects of RAD 140 With TRT

RAD 140, also known as Testolone, is a selective androgen receptor modulator (SARM). It selectively binds to your androgen receptors, much like testosterone, producing similar anabolic effects. Since it doesn’t convert into estrogen, it presents lesser known side effects such as water retention and acne. When one adds RAD 140 to their TRT dose, it potentially boosts the testosterone enhancement activity, thereby yielding better results.

Key benefits of RAD 140 during TRT

RAD-140 is known for its potential in muscle building, increasing lean mass and strength while reducing fat. Alongside, it doesn’t intervene with your hormonal production. Similar to natural testosterone, RAD140 doesn’t just increase muscle strength, but it also aids in protecting brain tissue and reducing the risk of benign prostatic hyperplasia (BPH).

How to properly add RAD-140 to a TRT regimen

Planning and starting a cycle with RAD-140 while on TRT requires careful analysis. To ensure safer outcomes and minimize potential side effects, you’d want to start with a low dose, around 5 mg per day, to assess your body’s reaction. If toleration is good, a gradual increase in dose can be considered, based on your body’s response and fitness goal.

Diagram showing how adding RAD 140 with TRT can enhance free testosterone levels.

Does RAD-140 lower TRT’s side effects?

Side Effects

TRT, or Testosterone Replacement Therapy, while beneficial, can produce certain side effects. RAD 140, thanks to its ability to lower SHBG levels, could potentially reduce these effects. Current user testimonies and ongoing research seem promising in this aspect.

While TRT might cause an increase in estrogen levels leading to water retention and gynecomastia, RAD-140 doesn’t convert into estrogen. This unique characteristic makes RAD-140 a valued component in a TRT cycle as it can possibly manage the estrogen levels.

Practical ways to control side effects when using RAD-140 and TRT

Monitoring blood and hormonal levels regularly, maintaining a balanced diet, getting enough sleep, and sticking to a prescribed consumption protocol is critical when using RAD-140 and TRT. These steps will ensure you reap the benefits while controlling potential side effects.

What is the best dosage for RAD-140 in a TRT cycle?


Finding your ideal RAD-140 dosage isn’t a one-size-fits-all process. It can vary from user to user based on multiple factors, including your body composition and overall fitness goals. Initial doses are usually low and often are gradually increased, but only under careful observation for any side effects.

An ideal starting point is 5 mg of RAD 140 with TRT. After a week, you can up the dosage up to 10 mg per day.

The implications of dose variation in RAD-140 during TRT

Overdoing or underdoing your RAD 140 dose during TRT can impact your results adversely. An unusually high dose (20+ mg a day) might not give the results you want and could lead to side effects. Sticking to the recommended dosage regimen is essential in achieving optimum results. You can read our guide on determining the best RAD 140 dosage here

Remember, bigger doses don’t always produce better results.

Effective TRT dosage protocols for optimum results

An effective testosterone dosage protocol that aims at maximum results in minimum time without compromise on your health is the key. Having a thorough understanding of your body and working with a healthcare provider knowledgeable in TRT and RAD-140 can pave the way to designing such an ideal protocol. In most cases, 200mg of test a week or less is suitable for TRT. 

How does RAD-140 affect TRT-induced muscle gains?

Muscle Gains

RAD 140 is known for its incredible muscle-building capability without the nasty side effects that come with most anabolic steroids. It’s currently under research, but many users report significant gains in muscle mass and strength.

Compared to other SARMS used in a TRT cycle, RAD140 has shown superior results in terms of lean muscle gains, fat loss, and overall anabolic to androgenic ratio. Its relatively higher muscle-building potential has made it highly favored among TRT users.

Other than RAD 140, similar compounds to stack with testosterone would be Anavar and YK11.

Case studies on RAD-140 and muscle gain during TRT

The case studies available to date suggest that RAD-140 has a remarkable role in promoting muscle gains during TRT. However, more extensive clinical trials are needed to substantiate these findings fully.

How RAD 140 raises free test via SHBG inhibition

What happens after you finish a RAD-140 TRT cycle?

Coming Off TRT

After you finish a RAD-140 TRT cycle, a well-planned PCT protocol is crucial. It helps restore your natural hormonal balance and can mitigate potential withdrawal symptoms. Please take note, monitoring is essential during this period.

Regular blood tests are among the most reliable ways to monitor your hormone levels after a TRT cycle involving RAD-140. In addition to this, taking note of physical changes or any symptoms can provide valuable insights into your hormonal profile.

Expectations after discontinuing RAD-140

Once you end your RAD-140 cycle, expect gradual changes. Some individuals may experience an immediate dip in strength and size, but the muscle gain with proper PCT and healthy lifestyle habits can be maintained over a long term.

In conclusion, adding RAD-140 to a TRT routine can help amplify the total benefits while managing the side effects. However, individual response can vary. Always consult with a healthcare professional before you begin your RAD-140 combined TRT cycle. Safety should always be your primary concern. Stay informed, stay safe!

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Frequently Asked Questions


Can RAD 140 and testosterone be stacked together?

Yes, RAD 140 and testosterone can be stacked together. However, it’s important to make sure this is done by a professional as RAD 140 can be suppressive. Also, ensure you monitor testosterone suppression and lipid profile regularly for a better experience.

What benefit can I get from adding RAD 140 to TRT?

One potential benefit is that RAD 140, besides boosting your testosterone levels, also helps increase muscle mass while reducing fat. It also tends to be less suppressive, which may make it a good addition to a TRT stack.

Is RAD 140 approved for human use?

At the moment, RAD 140 is not approved for human use. However, it’s widely used in the bodybuilding industry and research continues to learn more about its potential benefits.

What should I eat while on RAD 140 and TRT stack?

While on a RAD 140 and TRT stack, make sure you eat a balanced diet rich in cholesterol, which is crucial for overall hormonal balance. Foods like eggs, lean meat, and seafood can be beneficial.

Can RAD 140 affect my lipid profile?

RAD 140 can indeed affect your lipid profile, mostly because it can lead to insignificant changes in cholesterol numbers. Make sure to monitor your lipid profile regularly while on a RAD 140 and TRT stack.

Can adding RAD 140 to TRT suppress my testosterone levels?

Yes, adding RAD 140 to TRT can bring about testosterone suppression. That’s why it’s recommended to monitor your testosterone levels frequently and consider taking PCT after the cycle.

Is using pharma grade RAD 140 better for TRT?

Contrary to popular belief, there is no such thing as “pharma grade RAD 140”. SARMs are currently only available to be sold for research use. With that said, this may change in the future if it ends up being approved for pharmaceutical companies to market it human use. 

Is the total dose of RAD 140 and testosterone important in TRT?

Yes, the total dose of RAD 140 and testosterone is important in TRT. Getting the dosages right would ensure optimal benefits while reducing side effects. Therefore, always consult a professional for dosage advice.


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  2. Hwang, D. J., Kim, Y. W., Kim, D., Jeong, J. H., Chung, H. J., & Lee, J. H. “Selective androgen receptor modulators: in pursuit of tissue-selective androgens.” Current opinion in chemical biology, vol. 41, 2017, pp. 76-86.
  3. Yin, D., Xu, H., He, Y., Kirkovsky, L., Miller, D. D., & Dalton, J. T. “Pharmacology, pharmacokinetics, and metabolism of acetothiolutamide, a novel nonsteroidal agonist for the androgen receptor.” The Journal of pharmacology and experimental therapeutics, vol. 304, no. 3, 2003, pp. 1323-1333.
Chris Jackson
Chris Jackson

Chris Jackson, co-founder of Sarms.io, is a renowned fitness blogger, physique model, and evolutionary bioscience researcher specializing in SARMs (Selective Androgen Receptor Modulators). His extensive work, characterized by cutting-edge research and practical training advice, has made Sarms.io a leading source for accurate, credible information on performance enhancers. With a dedication to improving the understanding and application of SARMs in optimizing human performance, his contributions have not only expanded public awareness but also shaped the conversation around these substances. Chris's pursuit of knowledge and commitment to sharing it continue to inspire many in their fitness journeys.

  1. Do I need to PCT after Rad140 if I’m continuing my trt cycle for life. I’ve been on 130mg try for many years and want to add Rad 140 …

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