LGD 4033 vs Ostarine: Differences and Benefits Compared

There are a ton of ways to improve lean muscle mass and burn fat. Every now and then, bodybuilders like to use products that help them get there. Selective androgen receptor modulators or SARMs belong in that category. 

LGD 4033 or ligandrol is mainly used for bulking cycles. It binds to androgen receptors in the muscles and bones of the human body. This is one of the reasons scientists think it does not affect other organs like the liver and prostate. It is also believed to be unlikely that users might experience testosterone suppression from LGD 4033. However, there is little to no scientific data to prove this.

Ostarine or MK 2866 is better for cutting and beginners bulking cycles. This too stimulates androgen receptors and is able to target specific bones and muscles. While it is an unapproved drug, the underground fitness community swears by it. Ostarine also brings with it the possibility of increased levels of estrogen and testosterone suppression. But those who favor SARMs claim to have a workaround for it.

This post will compare LGD 4033 vs Ostarine. We’ll take a look at the main differences and how the results of each differ.

LGD 4033 vs Ostarine comparison
LGD 4033Ostarine
Common Usage:BulkingCutting
Side Effects:Mild/ModerateMinimal
Safe For Women:NoYes
Average Dosage:10mg/day25mg/day
PCT Recommended:YesNo
Anabolic Ratio:90:110:1

The Main Differences between LGD 4033 vs Ostarine

  • Ostarine was developed for muscle wasting and osteoporosis in patients with chronic diseases, whereas LGD 4033 was developed for maintaining muscle mass.
  • Ostarine can lead to an increase in estrogen levels, whereas LGD 4033 can lead to a decrease in globulin and testosterone levels.
  • Ostarine is a better choice for beginners and experienced users, whereas LGD 4033 is more for those who have done a few cycles of steroids or SARMs.
  • Ostarine is good for cutting cycles, whereas LGD 4033 is good for bulking cycles.

The Role of SARMs and Steroids

Here is the lowdown on SARMs and steroids, as promised in the beginning. SARMs and steroids are both illegal for different reasons. Here is the deal with SARMs. 

When testing on these products began, it was done on rats, mice and sometimes even monkeys. Those toxicology reports showed that SARMs have the ability to cause a range of cancers in the test subjects. So, they never proceeded to human trials and were banned instead. 

However, those who argue in favor of SARMs say that the animals were given a very high dosage and it was done for an excruciatingly long time. With this argument, they have been pushing for more research and testing on SARMs. 

So, these substances are available in the market as research products. Sportspersons often use these substances as performance enhancers even though it is banned by the World Anti-Doping Agency (WADA). Most of the SARMs are listed under the S1 Anabolic Agent category of the prohibited list.

Results with Ostarine

Ostarine is a SARM that is consumed in cycles. A typical ostarine cycle lasts from six to eight weeks. During this time period, it is advised that beginners take no more than 15 mg per day. If you have had previous experience, you can go up to 20 mg per day. In fact, if you have experience and want to mix other SARMs, you can consider taking 15 mg of cardarine per day. In that case, you must limit your ostarine intake to 10 mg a day.

A cardarine plus ostarine cycle of eight weeks helps the consumer lose an estimated five percent body fat and also gain muscle. Remember that proper training and diet is a key part of any SARM cycle. These cycles are also broken down into bulking and cutting cycles.

If you manage to keep the dosage and cycle under control, you will not experience testosterone suppression with ostarine. However, if you experience uncomfortable changes, it is best to stop your cycle and start post-cycle therapy or PCT. Trouble is to be expected if you do not procure the absolute high-quality SARMs. For that, you can browse through this collection.

Results with LGD 4033

Ligandrol or LGD 4033 is for the big boys. This is a SARM for those who have a little experience and are really looking to bulk up. Many users have reported a complete transformation from skinny to muscular. 

Like it is with all SARMs, those in support of ligandrol say that a safe dosage for a limited period of time has no side effects. But there is little to no scientific data to support or oppose these notions. Most of what we know about SARMs like ligandrol is through anecdotal evidence. Now, what does anecdotal evidence say?

Ligandrol can be used with something like cardarine which will help gain muscle. Users have reported having gained anywhere from eight to 10 pounds of muscle mass and having lost three to five percent body fat with cardarine. Of course, you need to eat and train well. If you take 15 mg of cardarine for six to eight weeks, keep your LGD 4033 dosage to 5 mg per day. At a safe dosage, you don’t need post-cycle therapy after an LGD 4033 cycle. But ideally, you must be prepared for it. The best way to do that is to get a blood test done before starting the cycle.

Which one is better for bulking?

No question, LGD 4033 is a much better SARM for bulking than Ostarine is because of it’s ability to target the androgen receptors in a stronger manner.

Which one is best for beginners?

Ostarine is a much better SARM for beginners than LGD 4033 is. Both are suitable for first cycles, but LGD 4033 is going to have a higher chance of side effects than Ostarine.

Can I stack LGD and Ostarine together?

You can, but it’s not the most efficient stack. If you’re bulking, you should be stacking LGD 4033 and MK 677. If you’re cutting, look into stacking Ostarine with Cardarine.

Parting Words

Ostarine is one of the better-researched SARMs and is being tested for its ability to help avoid muscle wasting in advanced-stage cancer and renal disease patients. Now, none of the SARMs out there have been approved for human consumption anywhere in the world.

As of 2020, China—the largest country to produce and import SARMs—has passed two new laws declaring a ban on these products. However, for now, they are still available as research products and the underground fitness community swears by their results.

So, a few companies have found a way to sell these substances in the black market. Before you start a cycle, be mindful that there is a certain amount of risk that comes with using unapproved drugs. It is important to remember that the best results come from eating well and training according to your dosage.

You should keep a written record of your dosage, cycle and how your body is responding to the SARMs. It is important to keep a record so that there is a log for your trainer or doctor to refer to in case of any complications.

If you do it right, you might just see the results you were hoping to see. Good luck.

Chris Jackson
Chris Jackson

Chris Jackson, co-founder of Sarms.io, is a renowned fitness blogger, physique model, and evolutionary bioscience researcher specializing in SARMs (Selective Androgen Receptor Modulators). His extensive work, characterized by cutting-edge research and practical training advice, has made Sarms.io a leading source for accurate, credible information on performance enhancers. With a dedication to improving the understanding and application of SARMs in optimizing human performance, his contributions have not only expanded public awareness but also shaped the conversation around these substances. Chris's pursuit of knowledge and commitment to sharing it continue to inspire many in their fitness journeys.

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