With the large variety of different SARMs available for sale, it can be hard to know which one to use in your next cycle. Two of the most popular SARMs for gaining muscle mass are RAD 140 (Testolone) and LGD 4033 (Ligandrol).
RAD 140 and LGD 4033 have a lot of similarities, but also some striking differences. In this article, we will compare the two and show you which one is the better option for your goals.
If you’d like to skip the reading and instead know my recommendation…
My Pick: LGD 4033
While RAD 140 is a great pick for those looking to gain size, LGD has a lot of advantages. It is just as strong, provides dryer muscle gains, and can be cycled longer. It is also 50% less expensive on average depending on the source. Click the button below to view our recommended sources:
The Main Differences Between RAD 140 vs LGD 4033
The main differences between RAD 140 vs LGD 4033 are:
- RAD 140 is better at building mass in a short time, whereas LGD 4033 produces more consistent gains over long cycles
- RAD 140 has significant androgenic activity, whereas LGD 4033 has mostly anabolic properties
- RAD 140 has an average cost of $60, whereas LGD 4033 costs $40 on average
Rundown of RAD 140 vs LGD 4033
LGD 4033 was created by Ligand Pharmaceuticals. Originally, they studied it’s ability to treat muscle wasting conditions. In 2018, Ligand sold the rights to the drug to Viking.
Initial studies done on Ligandrol show that it is highly anabolic. A 2010 study demonstrated that LGD 4033 promotes dose dependent gains in lean body mass. A 10.2% increase of body mass occurred in participants taking only 1mg a day.
Likewise, RAD 140 has similar origins. Radius Health created RAD140 to investigate it’s potential to treat muscle wasting disorders. Studies were also done to see if it could offer an alternative to men using TRT.
This study shows that even small doses (0.1mg/kg) of Testolone increase total body weight.
Comparing RAD 140 vs LGD 4033
These SARMs share a lot of characteristics which can make it difficult to decide which one is best. We’ve put together a table below that will help you compare the two side by side.
|LGD 4033||RAD 140|
|Best For:||Dry, consistent mass gains.||Quick mass and strength gains.|
|Half Life:||24-36 hours||15-20 hours|
|Side Effect Risk:||Minimal||Moderate|
|Molar Mass:||338.25 g/mol||393.8 g/mol|
|Solubility:||PG, DMSO, Ethanol||DMSO, Ethanol, PEG-400|
|Average Cost:||$45||$55 to $70|
RAD 140 Pros and Cons
- Rapid lean body mass gains
- Large increases of strength
- Very anabolic
- Potential of androgenic side effects
- More suppressive than other sarms
- Increased water weight
LGD 4033 Pros and Cons
- Consistent, dry mass gains
- Can be used for 12 week cycles
- High anabolic activity
- Some potential for side effects
- Not as strong mg per mg
RAD vs LGD For Lean Body Mass
LGD 4033 and RAD 140 are both good options when it comes to packing on size. They are highly anabolic drugs that allow users to experience rapid gains in lean body mass.
Ligandrol is an excellent choice for those who want to experience lean, dry gains. You can cycle it for up to 12 weeks at a time. Users report steady, consistent gains that are easy to keep after your cycle ends.
RAD140, however, is a better choice if your only concern is to add maximum size in the shortest amount of time. You should keep these cycles short, since Testolone causes more suppression than LGD.
Bottom line: Both are great for gaining mass. RAD produces faster results, but LGD is a better choice for long cycles.
Winner: RAD 140
Side Effect Comparison
Next up, let’s talk about side effects. Nobody likes having their cycle ruined by unforeseen issues.
RAD140 and LGD4033 are both SARMs. Thus, they have much less side effects than traditional old school steroids.
With that said, RAD 140 has much more androgenic activity than LGD 4033 does.
Androgenic activity means hair loss, deepened voice, prostate growth, etc… You know, the stuff you want to avoid when on cycle.
Ligandrol does not have nearly as much androgenic activity. Side effects such as hair loss are very rare and occur in a small amount of users.
Bottom line: LGD 4033 has a much better side effect profile than RAD 140 does.
Winner: LGD 4033
Which Causes More Suppression
All SARMs cause some level of testosterone suppression. RAD 140 and LGD are no different.
It is a fact that RAD causes much more significant suppression than LGD does.
For some people, that doesn’t matter. If you’re on some form of TRT (testosterone replacement therapy), you don’t need to worry about suppression.
Most people, though, don’t want to deal with have low T levels (even if it is temporary). Some of the side effects of low T are:
- Fatigue and low energy levels
- Hard time “getting it up”
- Lower libido and sexual desire
- Loss of motivation.
Not something I want to deal with, but that’s just me.
Bottom line: RAD140 causes more suppression.
Next up let’s look at common prices of both compounds. For this comparison, we averaged the prices from our list of stores with sarms for sale.
The average cost of ligandrol came in at $45. The average RAD/Testolone price varies between $55 and $70.
My Recommendation: LGD 4033
I’ll be completely honest, I love ligandrol. It’s an absolute gem of the SARMs world and is one of the most powerful mass gainers out right now.
When you compare it with RAD-140, it reigns superior in almost all aspects.
It is true that testolone is a stronger SARM on a milligram to milligram basis. But stronger doesn’t always mean better.
What good does a stronger SARM do you if you lack the energy to go to the gym? News flash, it doesn’t.
Now, of course there are some people that respond differently. I’ve reviewed bloodwork from people using both drugs and have seen it go both ways. I know of many people who swear by Testolone.
Ultimately, you should try both (seperately) and find out which one you like more. They are both fantastic options for gaining mass, size, and strength.
Buy Legit RAD 140 and LGD 4033
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How to Pick What SARM to Use
The most common question submitted on the SARMS.io comment section is “which sarm should I use?”. It’s a hard question to answer because it all depends on your goals.
On our homepage, you can use our free SARM matching tool to find out which SARM best suits your goals and body type. It is free to use and we are constantly tweaking the algorithm to make sure the results it gives are accurate.
You can find both online, but be careful where you shop. These two SARMs are faked quite often. We keep an updated list of trusted sarm sources that can help you find a legit source.
There’s no question that RAD140 is a stronger SARM. Stronger doesn’t always mean better though, since there are many things that factor in. You can read our full comparison to see which one we recommend.
RAD 140 has a lot more side effects than LGD does. Studies show that this is because RAD has more affinity for the androgen receptor.
Basaria, Shehzad, et al. “The safety, pharmacokinetics, and effects of LGD-4033, a novel nonsteroidal oral, selective androgen receptor modulator, in healthy young men.” Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences 68.1 (2010): 87-95.
Miller, Chris P., et al. “Design, synthesis, and preclinical characterization of the selective androgen receptor modulator (SARM) RAD140.” ACS medicinal chemistry letters 2.2 (2010): 124-129.
Chris Jackson is a fitness blogger, physique model, and co founder of SARMS.io. He received his degree in exercise physiology from the University of Miami in 2012 and now contributes to some of the largest mens fitness publications in the world.