Test Base for SARMs: A Full Guide to Selection and Use

If you’re exploring the world of Selective Androgen Receptor Modulators (SARMs) understanding the concept of a ‘test base’ is crucial. This term often pops up in fitness and bodybuilding forums, leaving beginners scratching their heads in confusion. Don’t worry – we’ve got you covered.

In essence, a test base for SARMs refers to supplementing with exogenous testosterone during your SARM cycle. It’s designed to prevent any potential side effects related to low testosterone levels that can occur due to suppression from using these compounds.

As we delve deeper into this article, we’ll explore why incorporating a test base might be beneficial for you during your SARM cycle. We’ll examine the pros and cons while providing some practical guidelines on how to effectively use it as part of your regimen.

Understanding Selective Androgen Receptor Modulators (SARMs)


Let’s dive into the world of Selective Androgen Receptor Modulators or SARMs. These substances have gained popularity in recent years, primarily within the fitness and bodybuilding communities. But what exactly are they?

Essentially, SARMs are a type of drug that can selectively stimulate the androgen receptors in your body. These receptors play a vital role in building muscle mass, among other things.

Consider this: your body naturally produces testosterone which binds to these androgen receptors to promote muscle growth. However, sometimes you might want an extra boost – that’s where SARMs come in. They mimic the effects of testosterone but with one key difference: they’re selective.

This selectivity means that unlike traditional steroids which affect all tissues equally (often leading to undesired side effects), SARMs only target specific tissues like muscles or bones. This could potentially minimize side effects while maximizing benefits – quite a promising prospect!

Here’s a quick rundown on some popular types:

  • Ostarine (MK-2866): Known for its mild nature and versatility.
  • Ligandrol (LGD-4033): Favoured by those looking to bulk up.
  • Testolone (RAD140): Believed to be one of the most potent options available.

As promising as SARMs sound, it’s not all about just popping a pill or two and expecting miraculous muscle gain. To maximize the benefits that SARMs offer while minimizing potential side effects, it’s crucial to consider their usage in conjunction with what’s known as a ‘Test Base’.

A test base acts as a stable, baseline source of androgens. Often this could be natural testosterone or other similar compounds. The idea behind using a test base while on a SARMs cycle is to combat possible testosterone suppression that might occur due to SARMs usage.

Constant levels of testosterone or similar androgens in your system during a SARM cycle ensure that functions dependent on these hormones continue to operate properly. Furthermore, incorporating a test base could potentially allow you to maintain the muscle and strength gains post the SARM cycle better.

Choosing an appropriate test base, understanding its benefits, and knowing the possible risks it might pose, are as critical as deciding to take SARMs. Thus, let’s delve deeper into the world of test bases for SARMs and discover how to harness their full potential.

How using a test base for sarms works (diagram chart)

Analyzing the Role of SERMs as a Test Base for SARMs


Let’s talk about using SERMs as a test base in a SARMs cycle.

SERMs, as their name suggests, are substances that can either block or activate estrogen receptors in different types of tissues. They’ve been used primarily to treat conditions like breast cancer and osteoporosis. But recently, they’ve found a new role in the world of performance enhancement.

When you’re using SARMs for bodybuilding or athletic performance enhancement, your natural testosterone production can take a hit. That’s where SERMs come into play. By utilizing them as a test base during your SARM cycle, you’re essentially providing your body with an external source of testosterone-like effects.

Here are some key points about this:

  • SERMs help maintain hormonal balance during a SARM cycle
  • They minimize side effects associated with low testosterone levels
  • They can aid in maintaining gains after the cycle ends

The use of SERMs as a test base for SARMs is still relatively new and research is ongoing to determine its efficacy and safety profile.

The best SERM to use as a test base for SARMs is definitely Enclomiphene. It provides a unique ability to stimulate natural LH and FSH levels without lowering IGF-1 too much. You may find that your total test levels actually go up if using enclomiphene with a mild sarm like Ostarine.

There’s also the option to run Clomid as a test base. Take 25mg a day alongside the SARM of your choice. I can personally attest to the effectiveness of running SARMs with SERMs. I’ve been able to cycle on and off SARMs while taking Clomid monotherapy for years at a time. Read our Clomid vs Enclomiphene article to learn more about choosing between the two.

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IGF-1 as a Test Base: Pros and Cons


When it comes to utilizing IGF-1 as a test base for SARMs, there are several aspects you need to consider. This protein hormone has both its advantages and drawbacks.

Starting with the positives, IGF-1 is well-known in the fitness world for its ability to support muscle growth. Here’s why:

  • It aids in hyperplasia, which is an increase in the number of muscle cells.
  • It boosts nutrient uptake into your muscles.
  • It enhances recovery times after workouts.

These benefits can certainly be appealing if you’re looking to bulk up or improve your performance at the gym. In fact, we’ve written about the muscle building properties of IGF-1 LR3 in the past.

I wouldn’t suggest staying on IGF-1 for more than 12 weeks, though. Long-term use of IGF-1 might lead to heart enlargement. While this substance does promote muscle growth, it doesn’t discriminate between different types of tissue – meaning that internal organs could also grow larger with extended use.

Here’s a quick summary table:

HyperplasiaHeart Enlargement
Enhanced Nutrient UptakeOrgan Growth
Improved Recovery Times 

Another drawback worth mentioning is that using IGF-1 as a test base for SARMs may not provide consistent results across all users due to genetic differences. Therefore, what works exceptionally well for one person might have less impressive effects on another.

Lastly, keep in mind that like any other supplement or drug out there on the market today – misuse can result in unwanted side effects such as low blood sugar levels or even nerve damage over time if dosages aren’t properly managed.

Deciding whether or not IGF-1 would make a good test base for your SARMs regimen depends largely upon weighing these pros and cons against your individual health status and fitness goals.

My suggestion to those looking to boost their IGF-1 levels is to simply use oral MK-677. It delivers long sustained pulses of IGF-1 and will counter act any potential negative impact on IGF you might be experiencing with SERMs as mentioned above.

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Analyzing the Use of Dehydroepiandrosterone (DHEA) as a Test Base


When it comes to SARMs, or Selective Androgen Receptor Modulators, you’re likely aware that having an effective test base is crucial. One popular choice among fitness enthusiasts and bodybuilders alike is Dehydroepiandrosterone (DHEA). Let’s delve into why DHEA is often chosen and what makes it stand out.

To start with, DHEA is a naturally occurring hormone in your body. It’s produced by both men and women in the adrenal glands. Its primary function? To act as a precursor for sex hormones like testosterone and estrogen. Now, when you’re using SARMs, they can suppress your natural testosterone production. That’s where DHEA steps in! By using DHEA as your test base while on a SARM cycle, you’re essentially helping to maintain healthy levels of these vital hormones.

Here are some key benefits:

  • Boosting natural hormone production: When on a SARM cycle, it’s important to keep your hormone levels balanced.
  • Improved strength & muscle mass: Aiding in protein synthesis, DHEA can contribute significantly towards muscle growth.
  • Enhanced mood: Healthy levels of sex hormones play an essential role in regulating mood swings.

However, just like any supplement or medication out there, DHEA isn’t without its potential side effects:

Potential Side EffectsDescription
Hormonal imbalanceOveruse might lead to excessive amounts of certain hormones
AcneIncreased sebum production could cause breakouts
Hair lossIn rare cases where individuals are sensitive

It’s always critical not just knowing about these potential risks but also paying attention to dosage instructions provided by professionals or manufacturers.

So yes! Using Dehydroepiandrosterone (DHEA) as a test base during your SARM cycle has its perks – from maintaining balance within your hormonal environment to assisting with muscle growth and even keeping those unwanted mood swings at bay! But remember – moderation is key here! You don’t want those pros turning into cons due to misuse or overuse.

4-Andro as a Test Base: Benefits and Drawbacks


Let’s move on to another incredible compound called 4-Andro or 4-DHEA.This compound serves as a potent test base due to its ability to convert into testosterone in your body. But is it all good news? Let’s delve into the benefits and drawbacks.

When you’re using 4-Andro, one major benefit is that it can significantly boost your muscle mass. It does this by increasing protein synthesis in your body – which means more muscle growth for you! Plus, there’s an added bonus: 4-Andro also aids in recovery post-workout. So, not only are you building more muscle, but you’re also bouncing back faster after hitting the gym.

While 4-Andro converts to testosterone quite efficiently (around 65% conversion rate), it may lead to less predictable hormone levels compared to direct testosterone administration.

One potential downside is water retention. Some users have reported bloating when taking this compound – something that might affect those chiseled abs you’ve been working on!

Boosts Muscle MassLess Predictable Hormone Levels
Enhances Recovery Post-workoutPossible Water Retention

Moreover, like any other supplement or drug out there – side effects aren’t unheard of with 4-Andro usage either. From acne breakouts to mood swings – these could potentially become part of your journey if not monitored properly.

  • Increased Acne
  • Mood Swings
  • Potential Liver Stress

Despite these drawbacks though, many find that the benefits outweigh them – especially when used responsibly under professional guidance or medical supervision.

Dianabol in Test Bases: A Thorough Exploration


Diving right into it, Dianabol is a name you’ve likely heard if you’re familiar with performance-enhancing compounds. It’s traditionally known as an oral steroid, but did you know it can also be used in test bases for Selective Androgen Receptor Modulators (SARMs)?

First off, let’s clarify what we mean by ‘test base’. In the context of SARMs use, a ‘test base’ refers to a compound that helps mitigate any potential testosterone suppression side effects. Now, why would Dianabol fit into this role? Let’s delve deeper.

The reason lies in its mechanism of action. Dianabol has potent androgenic properties and closely mimics the behavior of natural testosterone within your body. This means when you’re on a SARM cycle, using Dianabol as your test base could potentially offset some of those testosterone-dropping side effects.

However, there are important considerations to keep in mind:

  • Dosage: While beneficial at lower doses (think 10-30mg daily), higher doses might lead to increased side effects.
  • Cycle Duration: Shorter cycles (4-6 weeks) are recommended due to Dianabol’s hepatotoxic nature.

Remember though – everyone reacts differently! Some users report experiencing minimal side effects while others may encounter issues even at low dosages or short durations.

Here’s a quick comparison table highlighting these factors:

DosageCycle Duration
10-30mg daily4-6 weeks

With all this information laid out for you, it should be easier for you to decide whether incorporating Dianabol into your SARM routine makes sense for your specific goals and circumstances. Always remember – research thoroughly and consult with professionals before starting any new supplement regimen!

Overview of Human Chorionic Gonadotropin (HCG) as a Test Base


Next up we have Human Chorionic Gonadotropin (HCG). You’ve probably heard about it being used by guys to maintain their sperm count while on TRT, but did you know it’s also utilized as a test base for SARMs?

So what exactly is HCG? It’s a hormone produced in large amounts during pregnancy. But here’s where things get interesting: bodybuilders and athletes have found another use for this potent hormone – using it as an effective ‘test base’ while cycling Selective Androgen Receptor Modulators (SARMs).

By introducing HCG into your system while on SARMs, you’re essentially tricking your body into thinking it should keep producing testosterone naturally. As such, you’ll be able to maintain normal hormonal balance throughout the duration of your cycle.

But remember: HCG isn’t without its risks too. Some potential side effects include:

  • Mood swings
  • Gynecomastia
  • Headaches

It’s essential to consider these factors before deciding if using HCG is right for you.

The usage dosage varies from person to person and depends largely on individual goals and physical conditions. Generally speaking though:

Low end500 IU per week
High end1000 IU per week

My personal recommendation is 250 iu every other day. This is a higher dose than many recommend, and for good reason. Doses like this put you in the zone where an Aromatase Inhibitor is necessary.

I take Arimistane at 25mg a day and it takes care of the increased E2 levels that I get from the HcG.

Keep in mind that these numbers are just estimates; always consult with a healthcare professional before starting any new regimen involving hormones or supplements.

In short, the use of HCG as a test base can provide significant benefits, especially when cycling SARMs – but it must be done responsibly and under proper guidance.

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Oral Estrogen as a Test Base: An In-depth Review


Oral estrogen, also known as estradiol, is typically prescribed to treat menopause symptoms. But in recent years, bodybuilders have discovered its potential role in balancing hormone levels when using selective androgen receptor modulators (SARMs).

So why would you use oral estrogen? Here are some key reasons:

  • Hormone balance: SARMs can suppress natural testosterone production. Using an external source of estrogen helps maintain hormonal balance.
  • Preventing side effects: High doses of SARMs may lead to unwanted side effects like mood swings or loss of libido. Oral estrogen can help mitigate these issues.

However, it’s crucial not to rush into this without proper understanding and guidance. Overuse or misuse could result in negative health impacts such as blood clots or increased risk of certain cancers.

When considering dosages for oral estrogens with your SARM cycle, here’s what you should know:

1 – 2 mgDaily

Remember though, everyone’s body responds differently so always consult with your healthcare provider before starting any new regimen.

One final note – while the benefits might sound promising, it’s important to understand that the research around using oral estrogens alongside SARM cycles is still very much ongoing. So take caution when interpreting anecdotal evidence from online forums or personal testimonials.

Traditional Testosterone Injections as a Test Base: An Examination

Test C/E

Testosterone injections have long been the traditional test base for SARMs, or Selective Androgen Receptor Modulators. They’ve been seen as the gold standard in many circles. But are they really all they’re cracked up to be? Let’s delve into this topic and find out.

First off, what exactly is a testosterone injection? It’s a type of therapy that involves injecting synthetic testosterone directly into your body. This method can quickly boost your testosterone levels and help you gain muscle mass and strength.

But there are some downsides to consider:

  • Side effects like acne, hair loss, mood changes
  • Possible damage to liver or heart
  • Needles can be uncomfortable or painful

Now let’s look at how these injections stack up against SARMs:

 Testosterone InjectionsSARMs
Muscle GainHighModerate-High
Risk of Side EffectsHighLow-Moderate

From this table, it’s clear that while testosterone injections may provide faster results in terms of muscle gain, they also come with a higher risk of side effects compared to SARMs.

When it comes down to choosing between traditional testosterone injections and modern-day SARMs as your test base, it’s essential you weigh the pros and cons carefully. Remember that everyone’s body reacts differently to these substances. What works well for someone else might not work for you.

The key takeaway here is there isn’t one-size-fits-all answer when it comes down to using either method as a test base for SARMs – it largely depends on your personal goals and health status.

Choosing the Right Test Base for Your SARMs Cycle


Selecting the right test base during your Selective Androgen Receptor Modulator (SARMs) cycle is a crucial part of the process. The choice can greatly impact your experience, results and overall health status.

Harnessing the Power of Enclomiphene

Enclomiphene is considered the most suitable Selective Estrogen Receptor Modulator (SERM) to use as a test base. Following close behind in preference is Clomid at 25mg, which although effective, should be used cautiously as it could result in certain side effects at higher amounts.

Consider 4-Andro

4-Andro presents itself as an attractive oral test base, possessing a credible reputation among SARMs users. However, bear in mind that to achieve the desired effects, optimal dosing might be expensive.

The Viability of DHEA For Older Guys

DHEA stands as a promising contender, especially for older males venturing into the world of SARMs cycle. Its selection should not be overlooked, for it caters to the unique requirements of individuals advancing in age.

Making the Case for Standard TRT Injections

For those who are ready to commit to long-term use, standard Testosterone Replacement Therapy (TRT) injections could be your best solution. However, it’s worth noting that the idea of injecting themselves may not sit well with some users.

MK 677: An Effective Choice for IGF-1 Management

Incorporate MK 677 in your routine to counterbalance any suppression of Insulin-like Growth Factor 1 (IGF-1) caused by SERMs. This strategic approach not only paves the way for a balanced hormonal milieu but also promotes better body functionality and growth.

The blueprint to an effective SARMs cycle goes beyond merely acquiring products. It requires a careful selection of a test base, taking into account your health status, fitness goals, and personal preferences.

Tips for Safe and Effective Use of Test Bases with SARMs


Navigating the world of Selective Androgen Receptor Modulators (SARMs) can be complex. But don’t worry, we’ve got you covered. Here are some tips to help ensure your use of test bases with SARMs is both safe and effective.

First things first, always consult a healthcare professional before starting any new supplement regimen. They’ll guide you on dosage, potential interactions, and monitor your progress throughout.

Understanding what you’re taking is key. Ensure that you’re sourcing your SARMs from reputable vendors who provide third-party lab testing results. This way, you know exactly what’s in the bottle – no surprises!

When it comes to dosing, less is often more with SARMs. Starting low allows your body time to adjust and reduces the risk of side effects.

DosageSide Effects

Regular monitoring while using test bases with SARMs can’t be overstated either! Regular blood work will show how well your body is responding or if there’s cause for concern.

  • Weekly: Check weight and general wellbeing
  • Monthly: Blood pressure checks
  • Quarterly: Comprehensive blood work

Sticking to these guidelines won’t just make using test bases safer; they’ll also optimize their effectiveness by ensuring that you’re not overdoing it or missing out on vital health checks along the way.

And remember this golden rule – listen to your body! If something doesn’t feel right after starting a new supplement routine, contact a healthcare professional immediately. With careful planning and responsible usage, incorporating test bases into your routine alongside SARMs can truly enhance performance without compromising safety.

Reflecting on the Future: New Test Bases for SARMs on the Horizon

Future Developments

The future of test bases for SARMs (Selective Androgen Receptor Modulators) is undeniably exciting. You’re about to embark on a journey, exploring what lies ahead in this rapidly evolving field.

There’s an increasing interest in developing more potent and selective SARMs. These could potentially offer greater muscle-building benefits while minimizing side effects. It’s all part of the drive towards safer, more effective performance-enhancing substances.

  • Potent SARMs
  • Selective action
  • Enhanced safety profile

Researchers are working tirelessly to refine testing methods for these compounds. With new technology comes improved accuracy and sensitivity in detecting even trace amounts of these substances. This will be crucial as doping tests become increasingly stringent.

Finally, let’s not forget about the legal landscape surrounding SARMs use and distribution. As science progresses, so too does legislation need to evolve to regulate their usage appropriately.

Frequently Asked Questions


What is the best test base for SARMs?

The best test base for SARMs really depends on the individual’s body, goals, and the specific SARM they are using. However, a common choice is injectable testosterone due to its anabolic effect. Another choice is Dermacrine, a prohormone that converts into testosterone, often used as a test base. Dermacrine can be applied topically, eliminating the need to inject.

Why do I need to use a test base when using SARMs?

Using a testosterone base when you use SARMs minimizes common side effects like lethargy and reduces suppression of the body’s natural testosterone production. This keeps testosterone levels stable throughout your cycle. Without a test base, you may experience a decrease in free testosterone levels and a corresponding increase in SHBG (Sex Hormone Binding Globulin), which can lead to side effects.

How to choose test base supplements for SARMs?

When choosing test base supplements for SARMs you should look for products with the best quality ingredients that will help maintain your testosterone levels. Prohormone supplements like Dermacrine or injectable testosterone can be used as a test base. Be sure to research thoroughly and consider the suppressive nature of the SARM you’re using, as some SARMs like S23 are more suppressive than others.

Can LGD be used as a test base and what dosage is recommended?

LGD, specifically LGD 3033, is a potent SARM and is highly suppressive. It’s not usually used as a test base for other SARMs. The typical dosage for LGD 3033 is between 10-20 mg a day, but it’s safest and wisest to limit your use to 6 to 8 weeks.

What should I know about SERMs and SARMs?

SERMs (Selective Estrogen Receptor Modulators) like tamoxifen and clomiphene are often used in PCT (Post Cycle Therapy) after a SARMs cycle. They help to restart natural testosterone production and prevent estrogen conversion, reducing the risk of adverse side effects. However, taking the SERM should be done under supervision from a healthcare provider.

Why is PCT necessary after using SARMs?

PCT, or post cycle therapy, is needed after a cycle of SARMs to help your body regain its natural hormone balance. Because SARMs are suppressive, they can dampen the body’s natural testosterone production. PCT typically involves using drugs like SERMs, and can include supplements like Dermacrine to keep testosterone levels stable.

Is it possible to inject SARMs?

While it is technically possible to inject SOME SARMs, it is not the usual method of administration and wouldn’t be recommended without guidance from a healthcare provider. Instead, SARMs are mostly taken orally or through topical application in the form of gels or creams.

Are there any SARMs that do not require a PCT?

SARMs like Ostarine are less suppressive and might not require a PCT for some individuals, especially at lower dosages. However, it’s always safest to undertake a PCT after any SARMs cycle to ensure hormone levels return to normal. A blood test can give a clearer picture to guide this decision.

How to limit the suppressive effects of SARMs?

To limit the suppressive effects of SARMs, use a test base during your cycle to keep testosterone levels stable. Additionally, limiting the length of your cycle (ideally no longer than 8 weeks), adhering to the recommended dosage, and undertaking a thorough PCT afterwards will all contribute to minimizing suppressive effects.

Why is a test base also used for RAD?

A test base is also used for RAD (RAD-140), a highly anabolic SARM, because it can cause testosterone suppression. Using a test base helps to maintain stable testosterone levels throughout the cycle, minimising the potential side effects of that suppression. Dermacrine or injectable testosterone are common choices for a test base with RAD.


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  2. Musicki, Biljana, et al. “Testosterone Deficiency In Sickle Cell Disease: Recognition and Remediation“. Front. Endocrinol., vol. 13, 2022.
  3. Tipton, Kevin, et al. “Improving Muscle Mass: Response Of Muscle Metabolism To Exercise, Nutrition and Anabolic Agents“. Essays in Biochemistry, vol. 44, 2008, p. 85-98.
  4. Puia, Dragos, et al. “Effectiveness Of Clomiphene Citrate For Improving Sperm Concentration: a Literature Review And Meta-analysis“. Cureus, 2022.
  5. Rodriguez, Katherine, et al. “Enclomiphene Citrate For the Treatment Of Secondary Male Hypogonadism“. Expert Opinion on Pharmacotherapy, vol. 17, no. 11, 2016, p. 1561-1567.
  6. Shahid, Muhammad, et al. “Effectiveness Of Pharmacological Intervention Among Men With Infertility: a Systematic Review And Network Meta-analysis“. Front. Pharmacol., vol. 12, 2021.
  7. Tipton, Kevin, et al. “Improving Muscle Mass: Response Of Muscle Metabolism To Exercise, Nutrition and Anabolic Agents“. Essays in Biochemistry, vol. 44, 2008, p. 85-98.
  8. Wiehle, Ronald, et al. “Testosterone Restoration Using Enclomiphene Citrate In Men With Secondary Hypogonadism: a Pharmacodynamic And Pharmacokinetic Study“. BJU Int, vol. 112, no. 8, 2013, p. 1188-1200.
Chris Jackson
Chris Jackson

Chris Jackson, co-founder of Sarms.io, is a renowned fitness blogger, physique model, and evolutionary bioscience researcher specializing in SARMs (Selective Androgen Receptor Modulators). His extensive work, characterized by cutting-edge research and practical training advice, has made Sarms.io a leading source for accurate, credible information on performance enhancers. With a dedication to improving the understanding and application of SARMs in optimizing human performance, his contributions have not only expanded public awareness but also shaped the conversation around these substances. Chris's pursuit of knowledge and commitment to sharing it continue to inspire many in their fitness journeys.

1 Comment
  1. Bonjour, j’aimerais avoir ton avis sur ce cycle de sarms:
    -Semaine 1 à 8:
    Rad140 20mg/j
    Mk677 10mg/j (5j/7)
    Nac + tudca ( dosage a définir)
    -Semaine 3 à 8:
    Yk11 10mg/j
    Enclomiphene 12.5 mg/j
    -Pct semaine 9 à 12:
    Mk677 10mg/j (5j/7)
    Cardarine (10 à 20mg/j)
    Enclomiphene 12.5mg /j semaine 9 puis 6.25mg/j semaine 10

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