LGD 4033 Dosage Guide For Optimal Muscle and Strength Gains

Are you looking to enhance your training and workout performance? Do you want to make more progress in the next eight weeks than you have in your entire training career? LGD 4033 presents an androgenic advantage to your physique, helping you achieve the body of your dreams. You just need the right dosage.

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The reality is that if you want to look like the guys on the cover of Men’s Health, you need some chemical assistance. Yes, we know you’re training right and eating a strict diet, but you’ll never achieve that hard, ripped, muscular look without introducing drugs into your regimen.

Starting your enhanced journey is a challenging decision. There are so many choices out there; how do you settle on one compound? LGD 4033, also known as Ligandrol, offers you a great selection for a starter SARM that brings big results in the gym and the mirror.

What Is LGD 4033, and what does it do?

What is Ligandrol

Ligandrol (LGD 4033) is a collaboration between Ligand Pharmaceuticals and Viking Therapeutics. The medical industry initially developed Ligandrol for use as a treatment for muscle-wasting diseases and osteoporosis.

However, in the bodybuilding and fitness community, Ligandrol has a rich heritage as one of the most powerful SARMs. A six to eight-week cycle of this compound increases lean muscle mass while eliminating body fat. (1)

Ligandrol is the ideal starting point for a SARMs cycle, producing impressive effects in a few days after your first dose. 

What is the best LGD 4033 dosage for gains?


According to reviews from successful cycles, the best dose falls between 10mg to 20mg per day. The size of your dose depends on your previous experience with SARMs or anabolics. In this section, we’ll outline the correct dosing protocol for novice and experienced users.

Optimal Beginner Gains

If you’re new to SARMs, it’s a safer choice to start on the lower end of the range and build your dose. Beginning with a high dose might present side effects as your body adapts to the compound’s impact.

It’s a better choice to start with 5mg for three days and see how your body tolerates the drug. If no sides present, up the dose to 10mg, and wait for 10-days to assess the effects. You can up your dose to 15mg for the next four to six weeks at the two-week mark, depending on the side effects present on the cycle.

In the last week of your cycle, either week-6 or week-8, you can experiment with upping the dose to 20mg on workout days.

This protocol gives you the best first-time user experience of Ligandrol. Jumping into 20mg a day might cause unexpected side effects that put you off the drug.

LGD 4033 Dose for Optimal Advanced Gains

You can choose to run LGD 4033 solo for advanced users or stack it with other SARMs. We recommend running 10mg in week one for a solo cycle and upping the dose to 15mg in week two.

At the four week mark, increase your dose to 20mg until the end of your cycle. In the last week, either week-8 or week-10, you can up the dose to 25mg per day.

What can I stack on top of LGD 4033?


Advanced users can consider stacking LGD 4033 with other compounds to enhance the effect.

  • For a strength stack – RAD 140
  • For a cutting stack – Ostarine
  • For Strength and mass – YK11

The risk of side effects is greater, with multiple SARMs stacked together. Make sure you visit your doctor for bloodwork before and after and advanced cycle.

How do I set up a good Ligandrol cycle? Two examples

Example Cycle

“Cycling” is the process of administering anabolics or SARMs. The cycle means that your start at the beginning, and you eventually go full-circle to end up back where you start, using nothing. Cycle lengths are a hotly debated topic in the fitness and bodybuilding communities.

A cycle adds structure to your use of SARMs. You can’t just crack the top on a bottle of pills and haphazardly go to work in the gym. You need to plan every aspect of your cycle to ensure you have a successful and safe result.

We already discussed the dosage of LGD 4033, not let’s look at how you bring everything together to form your cycle. You’ll be measuring your progress in weeks, and there are structures for advanced and beginner cycles to suit your experience, let’s unpack each of them.

The Ideal Beginner LGD 4033 Cycle

  • Week 1 – 5mg for day-1 to day-3, with 10mg on day-4
  • Week-2 to week-4 – 10mg per day
  • Week-5 to week-8 – 15mg per day

Optional: Week 8 – 20mg on training days.

The Ideal Advanced LGD 4033 Cycle

  • Week-1 to Week-2 – 10mg per day
  • Week-2 to Week-4 – 15mg per day
  • Week 5 to Week 8 – 20mg per day
  • Week-8 to Week-10 -25mg per day

Optional: Advanced users can stack LGD 4033 with other SARMs to enhance results. Ostarine and RAD 140 are popular choices for combination stacks that supercharge results.

What are some of the side effects of LGD 4033?

Side Effects

Ligandrol does have a slightly suppressive effect on the endocrine system and the Hypothalamic Pituitary Testicular Axis (HPTA). As a result, you’ll need a PCT to help you restore the function of the HPTA after finishing your cycle. Typically, PCT can run from two to four weeks, depending on cycle length.

If you’re using high doses or stacking LGD 4033 with other SARMs, consult with your doctor for bloodwork tests before and after your cycle.

There are some suggestions that LGD 4033 has liver toxicity effects. (2) However, this is not a methylated compound. Ask your doctor to check your bloodwork for elevated liver enzymes post-cycle. Milk thistle can help with liver recovery from the adverse effects of SARMs use.

Some users report symptoms of high blood pressure in the first week of use. It takes time for the body to adapt to the compound, and BP may spike, but it fades away after the first few days of use. Elevated blood pressure might occur due to water retention in the early phase of the cycle as it adapts to LGD 4033.


LGD 4033 is a potent SARM used in both cutting and bulking cycles. It’s an excellent recomping agent for a body transformation, enhancing lean muscle mass while burning body fat. Your ideal dose of Ligandrol depends on your experience with the compound and SARMs in general.

If you’re a beginner, Ligandrol will produce impressive results at small doses. Start slow and build into your dose for a first-time Ligandrol experience that’s almost free from side-effects. Boosting your dose as a beginner is not a good idea, it’s better to stick to a small dose while your body adapts to a chemical edge.

Experienced SARMs users will gain plenty of benefits from LGD 4033. It’s a powerful compound and stacks well with other SARMs like YK11 and Ostarine. Regardless of whether you’re an experienced user or a novice with LGD 4033, you should always ensure you do bloodwork with your doctor at the beginning and end of your cycle.

How long does LGD 4033 stay in your system?

Ligandrol is detectible in urine for up to 21-days after your last dose. The World Anti-Doping Agency (WADA) put LGD 4033 on its banned list for performance-enhancing substances more than 10-years ago.

Is it better to take my dose in the morning or evening?

Ligandrol has a half-life of between 24-hours to 36-hours. Therefore, you only need one dose a day. Try taking your dose under the tongue an hour before your workout on training days (not including cardio days), and in the morning on non-training days.

Do I need a Post-Cycle Therapy (PCT) after cycling LGD 4033?

Yes, Ligandrol has a slightly suppressive action on the Hypothalamic Pituitary Testicular Axis (HPTA). As a result, you might experience low testosterone symptoms in the four weeks to eight weeks following the end of your cycle. An OTC PCT like a test-booster will be sufficient for speeding up your recovery of the HPTA to normal levels.

DISCLAIMER: The publishing website and author bear no onus of responsibility for your use of SARMs. We do not endorse or condone LGD 4033 or any other research chemicals for human consumption.


Chris Jackson
Chris Jackson

Chris Jackson, co-founder of Sarms.io, is a renowned fitness blogger, physique model, and evolutionary bioscience researcher specializing in SARMs (Selective Androgen Receptor Modulators). His extensive work, characterized by cutting-edge research and practical training advice, has made Sarms.io a leading source for accurate, credible information on performance enhancers. With a dedication to improving the understanding and application of SARMs in optimizing human performance, his contributions have not only expanded public awareness but also shaped the conversation around these substances. Chris's pursuit of knowledge and commitment to sharing it continue to inspire many in their fitness journeys.

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