YK11 Dosage for the Perfect Bulking Cycle (With Stacks)

Are you tired of not being able to put on size? It’s a frustrating experience when you’re doing everything right with your training and nutrition, and the results don’t show up. Chances are your genetics are holding you back from putting on size.

How does YK11 work when it comes to myostatin?

YK11 and Myostatin

Myostatin governs our body’s ability to pack on skeletal muscle. (1) When you reach your threshold, it gets harder and harder to make leans gains. However, with YK11, you have the chemical ability to move this myostatin threshold. 

YK11 is a potent myostatin inhibitor. This drug causes an increase in follistatin levels, bypassing the effects of myostatin on muscle hypertrophy. (2) By adding YK11 to your next bulking cycle, you get a chemical advantage to slapping on the size you desire. 

In this post, we’ll unpack everything you need to know about this drug and outline a few dosing guidelines for the perfect bulking cycle.

What results can I expect from a cycle of YK11?


YK11 is a potent myostatin inhibitor. You can expect it to take around three to four days to build to sufficient levels in your bloodstream. After a week, you’ll notice a difference in size, and the gains keep coming for the duration of your cycle.

According to Reddit user reviews, it’s possible to pack on up to 25lbs of muscle in a single cycle using this drug. The gains stick provided you use the right PCT protocol, and you can repeat your cycle after taking 10-weeks off.

YK11 is suitable for bulking cycles where you’re in a caloric surplus. The additional calories make the optimal growth environment for YK11. Stick to high amounts of protein above the 2-grams per-lb mark in your diet.

How much YK11 is required to lower myostatin?


If you’re looking to get the most out of your next bulking cycle, YK11 is a must-have compound for your cycle. This Myostatin inhibitor works well alongside other SARMs, or as a standalone product. YK11 is a powerful drug, and you’ll notice the effects after a few weeks.

When cycling YK11, it’s better to stay on the lower side of the dose and build your way into it. If you’re stacking with other SARMs, make sure you stick to a low dose.

YK11 is suitable for advanced users that understand how SARMs and other compounds affect their bodies. Newbies should avoid YK11 and start with a more forgiving SARM like RAD 140.

Basic Cycle Dosage

  • Week 1 to week 2 – 10mg per day
  • Week 3 to Week 4 – 15mg per day
  • (Optional) Week 5 to Week 6 – 20mg per day
  • (Optional) Week 7 to Week 8 – 30mg per day
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As you can see, you start small and build into a full dose over 8-weeks. This pyramiding strategy is effective at stacking on the gains throughout the entire 8-week cycle.

Avoid exceeding the 30mg mark with your daily dose of YK11. Doses above the 20mg mark are suppressive and require PCT to recover from the effects of the drug on the hormonal system.

Yk11 has a half-life of 12-hours in mice. We’ll use that as a guideline for dosing because nothing exists for human use. You’ll need to split your daily dose in two and take it 12-hours apart for the best results.

The optimal YK11 stack for increasing lean mas


YK11 is a great compound to stack with any SARM or AAS. This myostatin inhibitor helps you make the most out of growth cycles where you want to bulk as hard as possible and add plenty of size. However, it’s important to note that YK11 is an advanced drug and should not be part of a newbie cycle.

Newcomers should get their feet wet with other SARMs before they decide to dip their toe into the murky waters of YK11.

If you’re an advanced user, YK11 is a great choice for adding alongside your next cycle. Use it with other SARMs like RAD 140, LGD 4033, and Ostarine. For best results, stack with MK-677 for extra support and an easy PCT. Keep the dose on the lower side to prevent side effects when stacked with other SARMs or AAS.

An optimal stack for YK11 would include the following:

  • Week 1 to week 2 – YK11 10mg per day / LGD 4033 10mg per day / MK-677 20mg per day
  • Week 3 to Week 4 – YK11 10mg per day / LGD 4033 10mg per day / MK-677 20mg per day
  • Week 5 to Week 6 – YK11 15 mg per day / LGD 4033 15mg per day / MK-677 20mg per day
  • Week 7 to Week 8 – YK11 20mg per day / LGD 4033 20mg per day / MK-677 20mg per day
  • Week 9 to Week 12 – Mk-677 20mg per day only

Read more about SARMs bulking stacks >>

Do I need to use PCT after using YK-11?


YK11 is a suppressive compound. This myostatin inhibitor slows the function of the Hypothalamic Pituitary Testicular Axis (HPTA). While some evidence shows YK11 does not shut down testosterone production, it causes a substantial suppression.

Therefore, you’ll need to use a Post-Cycle Therapy (PCT) to help you recover the function of the HPTA after finishing your cycle. Without a PCT, your recovery is slow, and you’ll lose a significant amount of your gains waiting for the HPTA to turn the corner and bump up testosterone production to normal levels.

With a compound like YK11, the only way to ascertain the level of suppression on the HPTA is to visit your doctor for a bloodwork test. Your doctor draws a sample and sends it for testing. The results show your natural level of testosterone, and the doctor can make recommendations on the right treatment for your condition.

PCTs using OTC test-boosters might be suitable for mild solo cycles of YK11. However, if you’re stacking it with other SARMs or AAS, you’ll need a pharmaceutical-based PCT. When going for bloodwork after your cycle, remember to wait for 48-hours for the YK11 to clear from your system.

Closing Thoughts

If you’re looking to overcome the challenge of adding serious size to your frame, YK11 can help. This powerful myostatin inhibitor pumps up follistatin levels, allowing you to break through plateaus in your quest for size.

YK11 represents a new class of drugs presenting scientific breakthroughs in treatments for muscle-wasting disease. The popularity of YK11 spread through the bodybuilding community as research projects found administering the medication to mice produced a quadrupling in skeletal muscle mass.

With YK11, you can stack on slabs of muscle, with no ceiling on your gains. However, this is a powerful drug, and it remains untested in humans. There are reports of side effects like testosterone suppression, liver toxicity, and heightened aggression in users.

Other commonly asked questions about YK11


I heard YK11 comes from testosterone. Is YK11 a steroid?

YK11 is a derivative of dihydrotestosterone (DHY), a steroid used in the treatment of muscle-wasting disease. It shares a similar chemical composition as DHT but doesn’t produce the same action on the body. Technically, YK11 is not a steroid; it’s classified as a “myostatin inhibitor.” 

Does Yk11 show up on drug tests?

Yes. YK11 will show up on a drug test for up to 48-hours after your last dose. (3) WADA and athletic sporting bodies recognize YK11 as a performance-enhancing substance. Therefore, YK11 is prohibited for use by athletes in training and competition. 

Can YK11 cause gynecomastia?

There is no specific published science around YK11, and it being the cause of gynecomastia sides. However, according to user reviews, gyno may be a problem when stacking with AAS like testosterone. The effect of the drug might amplify estrogenic side effects in some users.

DISCLAIMER: The author of this post and the publishing website do not condone or recommend the use of YK11, AAS, or SARMs. This information is strictly for educational and research purposes only. 


Chris Jackson
Chris Jackson

Chris Jackson, co-founder of Sarms.io, is a renowned fitness blogger, physique model, and evolutionary bioscience researcher specializing in SARMs (Selective Androgen Receptor Modulators). His extensive work, characterized by cutting-edge research and practical training advice, has made Sarms.io a leading source for accurate, credible information on performance enhancers. With a dedication to improving the understanding and application of SARMs in optimizing human performance, his contributions have not only expanded public awareness but also shaped the conversation around these substances. Chris's pursuit of knowledge and commitment to sharing it continue to inspire many in their fitness journeys.

1 Comment
  1. Excellent article, thank you Chris. I have been on YK11 with my TRT for 3 weeks so far and am loving it so much. Using 10mg. Losing fat and also have hit PRs on my deadlift and squat.

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