Does MK 677 Cause Anxiety? What the Research Shows

MK 677, also known as ibutamoren or Nutrobal, is a secretagogue which promotes the secretion of growth hormone in the body. While it was initially developed to manage the symptoms of muscle wasting disorders like osteoporosis, muscular dystrophy, etc. the benefits of the increase in HGH (human growth hormone) and IGF-1 (insulin-like growth factor 1) is something that athletes and those looking to lose fat and build muscles find very helpful.

The secretagogue can have several other benefits for the body, including fat loss, better sleep quality and improved nails and skin, in addition to the building of fat-free mass. But like any other external substance, MK 677 has a few side effects.

While most of these side effects are mild and temporary, there are often questions about anxiety being one of the symptoms of MK 677. Let’s find out the truth.

Does MK 677 cause anxiety? Let’s take a look.

MK 677 Anxiety

To put it succinctly, yes, MK 677 can cause anxiety. However, this is not a very common occurrence and is possible only in people who are already prone to anxiety. Even among people who suffer from anxiety or are prone to developing symptoms of anxiety, it is not very common for MK 677 to cause anxiety.

Even among scientific studies, there is very little evidence to suggest MK 677 may induce anxiety. One of the possible reasons for this side effect may be that MK 677 often mimes ghrelin, also known as the “hunger hormone”, which has links to anxiety and depression. However, even these links have not been conclusively established and MK 677 essentially remains a growth hormone secretagogue more than a ghrelin agonist. 

If the MK 677 is of a high-quality composition, you should not feel any symptoms of anxiety if you are not otherwise prone to it. If you are not certain about what anxiety symptoms feel like, this may be a helpful primer.

How to avoid anxiety as a side effect when taking MK 677?


Having said the above, it is not unheard of that MK 677 causes anxiety and there are people who have reported experiencing anxiety directly after their dose. It is, therefore, best to take precautions against it even if the chances of experiencing this side effect are extremely low.

Often, people who are prone to anxiety may avoid taking MK 677 as they are afraid of it aggravating their symptoms of anxiety. However, if you take the right precaution and are responsible about how you are taking your ibutamoren, there should be no problem. 

The following are two key things you must keep in mind while taking MK 677, whether or not you are predisposed to having anxiety.

Start with a Low Dose

Firstly (and this is something you should practice anyway), it is important to start with a low dose and then determine the amount that works for you. If you are new to the secretagogue, it is advisable that you do this so you can determine the dosage that works for you best.

By starting with a low dose, you will also be easing your body into the effects of the secretagogue so it is prepared when the levels of the growth hormones do increase. If you start at a very high dose, you may experience anxiety simply because your body may be going through shock. So start slow, and gradually scale up your body’s ability to break the secretagogue down.

Be Sure to Get a High-Quality Product

The second and most important thing to do is to look for MK 677 of high-quality composition. Often, the anxiety may be resulting not from the MK 677 but from other substances that may be mixed in an impure composition.

This is, unfortunately, a rather common occurrence so it is advisable to purchase your MK 677 from a reliable source. If the ibutamoren you are taking is spiked, it can be dangerous in other ways as well, not just as a substance that causes anxiety.

💡 Top MK 677 Sources of 2024

Only buy your compounds from a trusted source. Check out the Verified Source list to find the best deals on high purity MK 677, Cardarine, Ostarine and more.

You do not know how the other substances will react to your body or what the composition of the secretagogue is. It is extremely important to be sure of the quality of the Mk 677. Take a look at our list of some of the best places to get your secretagogue fix. 

Conclusion about anxiety from MK 677

Final Thoughts

In conclusion, if you are taking real and high-quality MK 677, and you are not prone to anxiety already, there is no reason why you should experience it as a side effect. Even if you are prone to anxiety, it is a very rare side effect and does not happen to most people. 

There are also ways to avoid this side effect and take precautions against even this minute possibility. In other words, anxiety need not be a deterrent if you are looking to take MK 677. This is a rare side effect that does not outdo the fact that MK 677 does have pros that outweigh its cons.

Chris Jackson
Chris Jackson

Chris Jackson, co-founder of, is a renowned fitness blogger, physique model, and evolutionary bioscience researcher specializing in SARMs (Selective Androgen Receptor Modulators). His extensive work, characterized by cutting-edge research and practical training advice, has made a leading source for accurate, credible information on performance enhancers. With a dedication to improving the understanding and application of SARMs in optimizing human performance, his contributions have not only expanded public awareness but also shaped the conversation around these substances. Chris's pursuit of knowledge and commitment to sharing it continue to inspire many in their fitness journeys.

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