1-Andro Prohormone Guide: Benefits, Side Effects, Dosage, Results and more!

Searching for a powerful prohormone to boost your muscle gains and shred fat in 2023? 1-Andro, also known as 1-DHEA, 1-Androsterone, or 1-dehydroepiandrosterone, might be exactly what you’re looking for! This unique anabolic compound has gained a lot of popularity in the fitness world, and for a good reason. It comes with numerous benefits that will help take your physique to the next level.

The science behind 1-Andro is quite fascinating. This potent prohormone converts to 1-testosterone within your body, which is a highly effective anabolic hormone more than 2x as powerful as test. Due to this conversion, 1-Andro can dramatically increase muscle mass, strength, and performance while reducing body fat. Moreover, it’s considered less harsh on your system compared to other prohormones, leading to fewer side effects.

To get the most out of this powerhouse prohormone, it’s critical to understand how to use 1 Andro effectively in your exercise and diet routine. In this comprehensive guide, you’ll discover how to maximize its benefits for an amazing transformation. So, prepare to elevate your fitness game and start experiencing the remarkable results of 1-Andro!

Key Takeaways
  • 💪 1-Andro is a non-methylated prohormone that can improve lean mass, strength, and performance without estrogen or DHT side effects.
  • 🚀 Benefits of 1-Andro include increased lean muscle mass, strength, power, and fat reduction.
  • 💊 Potential side effects include mild headaches, changes in libido, and slight increases in blood pressure.
  • 🌐 1-Andro is legal in the United States but could show up on drug tests due to its conversion to 1-Testosterone.
  • 🔄 A typical cycle lasts 4-8 weeks, followed by post-cycle therapy (PCT).

Understanding 1-Andro Prohormone

What is 1-Andro?

1-Andro is a prohormone and precursor to 1-testosterone, a powerful hormone similar to testosterone. During this conversion, 1-Andro undergoes a two-step enzymatic process, first transforming into 1-androstenediol and then converting to 1-testosterone. This hormone allows you to put on lean muscle mass and offers several benefits.

Some of the key benefits of 1-Andro include:

  • Muscle growth: By increasing protein synthesis and nitrogen retention, 1-Andro supports the development of lean muscle mass.
  • Strength gains: Users often experience notable improvement in their overall strength and ability to lift heavier weights.
  • Reduced fat: Can stimulate fat loss by promoting a more anabolic state in your body.
  • No estrogenic side effects: Since it doesn’t convert to estrogen, you’re less likely to experience water retention and gynecomastia.
  • No DHT conversion: 1-andro does not convert to DHT, making it reasonably hair friendly

Though it offers various benefits, there are also some potential side effects associated with the use of 1-Andro Prohormone. Keep in mind that the severity of these side effects primarily depends on individual factors like genetics and the dosages taken.

Possible side effects of 1-Andro may include:

  • Suppression of natural testosterone
  • Decreased libido
  • Lethargy or fatigue
  • Hair loss
  • Aggression
  • Elevated liver enzymes

We’ll talk more about 1-andro side effects later in this article. We’ll also provide some tips to prevent side effects from happening in the first place. But first, let’s discuss more about how this anabolic precursor works in the body.

Diagram showing the mechanism of action of 1-Andro in the body

How does 1-Andro work and what are it’s main benefits?


1 Androsterone is unique because it’s a non-methylated prohormone, which means it won’t cause liver toxicity like some other prohormones. So, what’s the science behind its effectiveness?

When ingested, 1-Andro converts into 1-Androstenediol, then into 1-Testosterone. This process begins with the initial conversion of 1-Andro to 1-Androstenedione, catalyzed by an enzyme called 3b-HSD. Next, the 1-Androstenedione is converted to 1-Testosterone by the enzyme 17b-HSD.

1-Testosterorone is an incredible steroid in it’s own right. In fact, it’s highly sought after in the underground market in it’s injectable form. It has an anabolic potency 2x that of testosterone. 

Another noteworthy benefit of 1-Andro is its non-aromatizing nature. In simple terms, it doesn’t convert into estrogen, which spares you from water retention and bloating issues often associated with other prohormones. This also means that you’re less likely to experience gynecomastia, a condition where men develop breast tissue due to excessive estrogen levels.

A growing number of studies and anecdotal evidence support the use of 1-Andro for its potential performance-enhancing effects. For example, a 2013 study published in the Journal of Applied Physiology, Nutrition, and Metabolism revealed that 1-DHEA intake led to:

  • Lean body mass increase: +4.3%, vs. -0.2% for placebo
  • Leg press strength gain: +21.3%, vs. +14.8% for placebo
 Lean Body Mass ChangeLeg Press Strength Gain
1-DHEA Group+4.3%+21.3%
Placebo Group-0.2%+14.8%

The table below provides a general overview of the benefits associated with 1-Andro:

Muscle growthIncreases protein synthesis and lean muscle mass
Fat lossEnhances metabolism and inhibits fat-storing enzymes
Workout performanceBoosts energy levels and endurance

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Dosage Recommendations for 1-Andro


If you’re new to prohormones or have limited experience, you’ll want to start with a conservative dose. This approach helps minimize potential side effects and allows your body to adjust to the supplement.

  • Recommended dose of 100-200 mg per day
  • Divide the daily dose into two equal parts, taking one in the morning and the other in the afternoon
  • Cycle length should be 6-8 weeks

Advanced Users

For those with extensive experience using prohormones, you may opt for a higher dose to maximize gains. However, it’s important to keep potential side effects in mind and carefully monitor your body’s response.

  • Daily dosage can range from 200-400 mg
  • Split the dose into two equal parts, with one in the morning and the other in the afternoon
  • Cycle length should be 8-12 weeks
1-Andro / 1-DHEA Dosage Recommendations

Stacking 1-Andro with other compounds


When it comes to enhancing your workout routine and building muscle, stacking 1-Andro with other anabolic compounds can bring significant results. Here, you’ll find insights on the best ways to stack 1-Andro and how it can support your fitness goals.

Some compounds that stack well with 1-Andro include:

  • 4-Andro: This prohormone acts as a precursor to testosterone and stacks nicely with other andro compounds. This stack is used for supporting increased muscle growth, enhancing recovery, and improving overall athletic performance.
  • SARMs (Selective Androgen Receptor Modulators): These can support increased muscle mass and strength while simultaneously reducing body fat. They work by selectively targeting androgen receptors in the body, aiming to achieve steroid-like gains without the androgenic effects.
  • 19-Nor-Andro: This potent prohormone helps increase lean muscle mass and overall strength. It also supports rapid recovery, aids in reducing inflammation, and may even improve joint health.
  • Cycle support: There are plenty of good brands out there. The most important thing is that you are taking a cycle support supplement to help protect your liver while on cycle.

Potential Side Effects of 1-Andro

Side Effects

When taking a 1-Andro prohormone, it’s essential to be aware of the potential side effects. While it’s a legal and milder alternative to steroids, you should still consider some possible side effects that may occur during your 1-Andro cycle. Below, we’ll go over a few of those side effects.

It’s important to note that 1-Andro converts to 1-testosterone in the body, a powerful anabolic hormone. This conversion may affect your body’s natural hormone production. Some of the possible hormonal side effects of using 1-DHEA prohormones include:

  • Alteration of cholesterol levels
  • Increased blood pressure
  • Decreased natural testosterone production
  • Potential liver stress
Side EffectKnown Impact
CholesterolAltered Levels
Blood pressureIncrease
TestosteroneDecreased natural production
LiverPotential stress

Your workout and diet play a significant role in minimizing these effects. Ensure that you’re maintaining a healthy balance of muscle building and cardiovascular training, as well as a diet rich in clean, nutritious foods. Additionally, it’s recommended to monitor your liver health while taking 1-Andro, consuming liver support supplements to mitigate potential stress adequately.

Another aspect of 1-Andro usage is its impact on fat loss. While many users report positive gains in muscle mass and strength, there’s also a likelihood of increased fat loss. This reduction can lead to a leaner physical appearance, but it may also potentially:

  • Cause joint pain or dryness
  • Affect mood
  • Lead to fatigue or exhaustion
  • Cause headaches

To address these issues, ensure you’re staying well-hydrated, consuming sufficient healthy fats in your diet, and managing your exercise intensity responsibly.

While 1-Andro is generally considered a safer alternative to anabolic steroids, it’s not without risks. Any supplement that affects your hormones should be taken with caution. Monitor your body, and if you experience any severe side effects, discontinue use and consult a medical professional.

PCT and Cycling 1-Andro Prohormone

Post Cycle Therapy

When you’re considering using a prohormone like 1-DHEA (1-Andro), it’s essential to plan for Post Cycle Therapy (PCT) and understand the proper way to cycle it. PCT helps restore your body’s natural hormonal balance, while cycling ensures you give your system adequate time to recover. Let’s delve deeper into these critical aspects of using 1-Andro.

Post Cycle Therapy

PCT plays a vital role in helping your body regain its natural hormonal equilibrium after using anabolic compounds like 1-Andro. By doing so, you can maintain the gains while minimizing potential side effects such as:

  • Suppressed natural testosterone production
  • Mood swings and irritability
  • Low libido

PCT usually involves using a combination of over-the-counter supplements or prescription medications that help boost your natural testosterone production and balance other hormones. Some effective options for PCT after a 1-Andro cycle include:

Don’t skip post cycle therapy, even if you have to opt for an over the counter product. If you can’t access Enclomiphene or other SERMs, look for a product containing at least 1,000mg of Fadogia Agrestis. It’s one of the only natural supplements out there that can actually work as a PCT on it’s own. You want to recover your natural testosterone levels as quickly as possible after completing a cycle.

Cycling 1-Andro Prohormone

Adhering to an on-cycle and off-cycle period will help reduce the risks associated with prolonged hormonal imbalances. Here are some guidelines for cycling 1-Andro:

  • On-cycle period: Typically, 1-Andro cycles last between 4-8 weeks. During this time, you’ll consume the prohormone as recommended by the manufacturer or under the guidance of a professional.
  • Off-cycle period: After completing the on-cycle phase, you should go for an off-cycle phase, which usually lasts for the same duration as the on-cycle. This allows your body to recover and restore its natural hormone balance.

To further improve your 1-Andro experience, consider these additional tips:

  • Stay hydrated
  • Maintain a proper diet rich in high-quality protein sources
  • Incorporate resistance training targeting different muscle groups
  • Practice compound lifts such as bench press and deadlift
  • Get sufficient sleep for optimal recovery

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User Experiences and Real Results


Many users claim to have experienced significant muscle gains and improved body composition while using 1-DHEA. Notably, they’ve found it to be helpful in:

  • Increasing lean muscle mass: Users have noted substantial improvements in their muscle definition and overall muscle tone after just a few weeks of incorporating 1-Andro into their routine.
  • Enhancing strength and performance: People have observed increased strength levels and improved athletic performance, enabling them to push harder during workouts and achieve better results.
  • Reducing body fat: Along with muscle gains, some users have reported reductions in body fat after using this prohormone. This is likely due to its anabolic effects and its ability to optimize the muscle-to-fat ratio in the body.

While individual user experiences will vary, generally, 1-DHEA has been seen as a potent and effective anabolic compound. Here’s an overview of the typical results reported by users:

TimeframeMuscle GainStrength IncreaseFat Loss
4-6 weeks5-10 lbs20-30%1-3%

Keep in mind that these results strongly depend on factors such as diet, training intensity, and individual response to the prohormone.

Additionally, combining 1-Andro with a well-balanced diet and a good exercise regime maximizes the potential benefits. It should be noted that while 1-Andro is not a magic solution for instant muscle gain and fat loss, it has proven to be an effective asset in building the body you desire.

In summary, users of 1-DHEA have shared some impressive results:

  • Increased lean muscle development
  • Enhanced strength and athletic performance
  • Reduced body fat

These benefits, when combined with a focus on proper nutrition and consistent workout routines, can help you significantly improve your physique and attain your fitness goals.

Frequently Asked Questions

1-Andro FAQ

What is 1-Andro and how does it work?

1-Andro, short for 1-Androsterone or 1-DHEA, is a potent prohormone that converts into 1-testosterone in the body. It is known for its muscle-building and fat-reducing properties. When consumed, it can increase muscle size similarly to steroids, without the typical side effects associated with anabolic steroids.

What are the potential benefits of using 1-Andro?

1-Andro is known for its ability to increase lean muscle mass, strength, and power. It can also help reduce body fat, making it a popular choice among fitness enthusiasts and bodybuilders seeking a lean, toned physique.

Are there any side effects associated with 1-Andro?

Some potential side effects of 1-Andro include mild headaches, changes in libido, and slight increases in blood pressure. However, these side effects are typically mild and can often be managed by adjusting the dosage or supplementing with food. It’s also worth noting that 1-Andro doesn’t convert to estrogen or DHT, so you won’t have to worry about side effects like water retention or gynecomastia.

Is 1-Andro legal and can it be detected in drug tests?

In the United States, 1-Andro is legal and can be purchased and used without any legal concerns. However, the legality of prohormones can vary by country. If you’re an athlete, it’s important to be aware that 1-Andro may show up on drug tests because it converts to 1-Testosterone in the body.

How should 1-Andro be used for optimal results?

The recommended dosage of 1-Andro can vary depending on the specific product and your individual goals, but a common starting point is around 100-200mg per day. A typical 1-Andro cycle lasts 4-8 weeks, followed by a post-cycle therapy (PCT) period to help your body recover and maintain the gains you’ve made. Many users find it beneficial to split their daily dosage into two parts, taking half in the morning and half in the evening. Some also choose to take one of their doses before a workout for an extra boost.

Wrapping Up: Is 1-Andro Right for You?


After exploring the world of prohormones and gaining insights into 1-DHEA, it’s time to determine if 1-Andro is the right choice for you. You’ve learned about its potential benefits and side effects; now, it’s crucial to weigh those factors against your individual goals and preferences.

Consider the following points when deciding if 1-Andro is suitable for your needs:

  • Are you in search of a product to enhance muscle growth and strength? If you’re looking for an anabolic edge, 1-Andro may have the potential to deliver results.
  • Do you aim to decrease body fat, while preserving muscle mass? 1-Andro can help with this objective, as it’s known for promoting fat loss.
  • Are you prepared to tolerate potential side effects linked to prohormone use? While not as harsh as some other compounds, 1-Andro can still cause unwanted effects such as lethargy, joint pain, or reduced HDL cholesterol. It’s essential to monitor and adjust dosages accordingly, as well as follow proper post-cycle therapy.

In conclusion, 1-Andro can be a powerful prohormone for those seeking to build muscle and shed body fat. It’s essential to do your research, consult with a medical professional, and weigh the benefits against potential risks. Only then can you make an informed decision about whether this potent compound is the right fit for your fitness journey.


  1. Frye, Cheryl, et al. “Androgens With Activity At Estrogen Receptor Beta Have Anxiolytic and Cognitive-enhancing Effects In Male Rats And Mice“. Hormones and Behavior, vol. 54, no. 5, 2008, p. 726-734.
  2. Komarapuri, Shirisha, et al. “Synthesis Of 19-trideuteratedent-testosterone and The Gabaareceptor Potentiatorsent-androsterone Andent-etiocholanolone“. J Label Compd Radiopharm, vol. 51, no. 14, 2008, p. 430-434.
  3. Walton, Melanie, et al. “7 -Methyl-19-nortestosterone (Ment) Vs Testosterone In Combination With Etonogestrel Implants For Spermatogenic Suppression In Healthy Men“. Journal of Andrology, vol. 28, no. 5, 2007, p. 679-688.
Chris Jackson
Chris Jackson

Chris Jackson, co-founder of Sarms.io, is a renowned fitness blogger, physique model, and evolutionary bioscience researcher specializing in SARMs (Selective Androgen Receptor Modulators). His extensive work, characterized by cutting-edge research and practical training advice, has made Sarms.io a leading source for accurate, credible information on performance enhancers. With a dedication to improving the understanding and application of SARMs in optimizing human performance, his contributions have not only expanded public awareness but also shaped the conversation around these substances. Chris's pursuit of knowledge and commitment to sharing it continue to inspire many in their fitness journeys.

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