Cardarine Side Effects – When Should You Be Worried?

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A review of cardarine side effects you should look out for.

It’s three weeks into your diet, and things aren’t going as you planned. You’re behind on your weight loss goals, and that stubborn fat around the love handles and glutes isn’t going anywhere. 

If you’re planning to get on stage or hit the beach before the end of summer, you’re going to need to fast-track your progress.

SARMs present you with a way to supercharge your fat loss and ramp up your gym performance. Relax, SARMs aren’t steroids, but they are chemical compounds that deserve your respect. With Cardarine, you get an androgenic edge to your training to reach your physique goals faster.

GW-501516 is a potent compound assisting physique athletes in attaining a show-stopper physique that’s hard, grainy, and vascular.

These results sound great, right? A compound that gives you all the benefits of using steroids or thyroid and asthma drugs, without the side effects.

If it sounds too good to be true, it probably is. In this post, we’ll unpack everything you need to know about Cardarine. Are there side effects? Should you worry about them? We’ll reveal the information to keep you safe during your GW-501516 cycle.

What is Cardarine, and How Does It Work?

Cardarine is an interesting compound, known as a PPAR-delta activator. Also known as “Endurobol,” this SARM is a collaboration between GlaxoSmithKline and Ligand in the 90s. 

The drug’s initial use was for helping people with the treatment of metabolic disease that leads to the development of prostate and colorectal cancers.

However, the drug never made it to market, and the bodybuilding community turned onto it as SARMs gained widespread popularity and use.

  • Raise metabolic rate for faster fat burning results
  • Eliminate stubborn fat deposits
  • Enhance recovery
  • Reduce insulin resistance
  • Reduce LDL profiles for heart health
  • Enhance heart health and vascularity
  • Maintain lean muscle and reduce inflammation
  • Enhance stamina and energy levels throughout the day

GW-501516 works on the body using two mechanisms. It binds to PPAR-delta at a cellular level, and activates cells, stimulating the genes necessary for energy production.

This effect makes Cardarine the ideal choice to add to a cutting cycle for additional support. When dieting, you’re using a caloric deficit, allowing the body to metabolize body fat for energy. However, the further you go into a diet, the more your metabolism slows due to the reduced calories.

Most people must raise the calorie limit from time-to-time using cheat meals or breaks in their dieting program. This break and introduction of more calories get the metabolism ramped up and ready for the next dieting session.

With Cardarine on your side, you don’t experience this metabolic slowdown at the six to the eight-week mark of your diet. The drug helps to keep your furnace running hot for the length of your diet.

💡 Always buy SARMs from a reputable source like the ones found on the Source List >>

What Is the Best Dose for a Cardarine Cycle? 

When starting your Cardarine cycle, the dosage you use depends on your experience using anabolic or androgenic compounds. If this is your first SARMs cycle, you need to take it easy in the early weeks. 

GW-501516 is a potent compound offering impressive results. Therefore, it’s easy to get carried away with your dose when you get such outstanding progress delivered to your doorstep with this SARM.

Start your Cardarine cycle using 10mg per day. Over the next seven to ten days, track your progress with the drug in a journal. Record your feeling of well-being, performance in the gym, and any noticeable sides.

If at day-7, you’re feeling confident, and you can feel the drug working, step up the dose by 5mg. Run this protocol for ten days, and then up the dose by 5mg again if you feel up to it. Avoid exceeding the 20mg mark, as it may start to cause complications, and sides may appear.

How Long Do I Cycle with Cardarine?

Along with your dose, the length of your cycle is an important factor for newbies to consider. For your first cycle, you should look at four to six weeks maximum. This choice of cycle length won;’ suppress your natural testosterone at the recommended dose.

Extending your cycle is not a good idea. All SARMs, even Cardarine, has a slightly suppressive effect on the Hypothalamic Pituitary Testicular Axis (HPTA). Therefore, the longer you stay on, the harder your recovery.

However, experienced users might want to extend their cycle to 8-weeks for the best results. Experienced users know the best PCT protocol for their bodies and how to recover as fast as possible from the use of these compounds. Remember to do your PCT when coming off Cardarine.

Do I Need a PCT with Cardarine?

Cardarine does not act on the same pathways as Anabolic Androgenic Steroids (AAS). Therefore, it does not have the same suppressive effect on testosterone production. As a result, you don’t require an extensive PCT using drugs like Nolvadex and Clomid.

However, all SARMs have some sort of impact on the CNS and the Hypothalamic Pituitary Testicular Axis (HPTA). Adding a PCT using OTC test-boosting supplements can be advantageous in speeding up your recovery.

What are the Side Effects of Cardarine?

Now for the good news! According to reports, there are no know side effects from using Cardarine. Yes, that’s right, there’s nothing to be afraid of with this compound. Some will cite the research showing that Cardarine causes cancer in mice, but to date there hasn’t been ANY reported human issues.

Cardarine is not methylated, so it doesn’t have any harmful impact on your liver like prohormones and oral AAS. There is no water retention with GW-501516, making it suitable for cutting as it doesn’t hold back any water.

The lack of water retention means there’s no elevation in your blood pressure and no risk of enlargement of the heart’s left ventricle.

It’s important to stick to the dosage guidelines when using Cardarine. Ensure you don’t exceed the maximum recommended dose for your experience, or you might start to notice mild sides appear.

💊 Which SARM Is Best For Your Goals? Take the quiz:


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SARM Picker Quiz
Your Result: Ostarine
Ostarine is an easy, consistent way to improve your physique. It's mild and can be used for both bulking and cutting. Women can safely use this SARM. New users of SARMs should start here. TEST >>
Your Result: LGD 4033
LGD 4033 is a reliable bulking agent that can help you pack on dry mass. It has very little side effects and can be ran for 8 weeks at a time. It stacks well with other SARMs and can be used to preserve mass while on a cut. Stack with RAD 140 for huge gains or with Cardarine to help melt off some extra fat while you bulk.
Your Result: RAD 140
RAD 140 is arguably the most powerful bulking SARM that currently exists. It does have a higher side effect profile than Ostarine or LGD 4033, but many feel that it is worth it. It is a staple in the advanced bulking stack. You can take it alongside LGD 4033, MK 677, and YK 11 to gain serious amounts of lean body mass in minimal time.
Your Result: Cardarine
Cardarine is not actually a SARM, but it is often referred to as one. It's main ability is to encourage rapid loss of bodyfat and increased endurance. It is a staple for many bodybuilders who are prepping for a show and need to lose excess body fat. Cardarine is best for those who are already doing cardio and want the ability to feel like they can go forever. Since it doesn't have any androgenic effects, females can safely use it.
Your Result: MK 677
This growth hormone secretagogue is a must add to any bulking or cutting stack. MK 677 increases the amount of HGH and IGF-1 that your body produces. Since it works by helping your body increase it's natural levels, you do not need to cycle off MK 677. It has zero notable side effects other than water retention. MK 677 works best when stacked with SARMs such as RAD 140 and LGD 4033 for a bulk, and Ostarine / Cardarine for a cutting cycle. MK 677 really shines in older users who have started to experience lower HGH levels. It can also be used by women safely.
Your Result: SR 9009
SR 9009 is a powerful SARM that has the ability to rapidly melt away excess bodyfat. It works by simulating your body's response to exercise. Users typically result large amounts of weight loss with an increase of body fat. Stack it with Cardarine for the ultimate cutting stack or use with Ostarine to lean bulk.

Almost there! View your results:

Wrapping Up

Cardarine is a useful drug for fast-tracking the results of your diet. If you’re six weeks out and lagging in your progress, Cardarine can help get you on track. It’s an effective cutting agent for the stage or the beach, and you’ll see results fast.

Cardarine is a potent SARM with little to no side effects. If you are concerned about adding it to your protocol, start with a low dose, and work your way up. It’s important to let your body recover after any SARMs cycle. Remember to complete your PCT and take the same time off as you spent on the cycle before starting a new one. 

Speak to your doctor and arrange a bloodwork panel before you start your cycle. This strategy ensures your doctor has a baseline reading of your natural homeostatic state before embarking on your chemically-enhanced journey.

Cardarine Side Effects FAQ

Can Cardarine help me build muscle?

Cardarine helps to raise metabolic rate and boost fat burning. Therefore, most people use it in conjunction with a caloric deficit. GW-501516 can help preserve muscle mass when cutting, helping you maintain your lean muscle mass instead of watching it waste in the mirror.

Can Cardarine cause cancer?

Research shows that Cardarine promotes an environment for the growth of cancer tumors. However, there is no evidence showing that the use of Cardarine causes cancer in humans. If you’re dealing with cancer, make sure you speak to your doctor and arrange treatment, stay away from SARMs. Read my article about cardarine and cancer.

Does the FDA approve Cardarine?

Cardarine is not approved for use in humans by the FDA. GW-501516 has a classification as a “research chemical.” Therefore, it is not suitable for use in humans, much like prohormones and other muscle-building compounds.

DISCLAIMER: The hosting website and the author of this article have no onus of responsibility on how you use the information in this post. We do not condone or recommend the use of SARMs, and you use these compounds at your own risk.


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